Bentham Science Publishers

Insulin resistance is the main factor involved in the occurrence of the metabolic syndrome and later development of type2 diabetes. Despite decades of research on hormone's target tissues and the identification of most diverse candidates, the factors responsible for insulin resistance are still largely undefined. There is also a large discrepancy between in vitro and in vivo insulin sensitivity. Finally it is increasingly demonstrated that insulin resistance is found very early in life, long before metabolic syndrome is established. In search for commonalities, this book deals therefore with a new hypothesis considering microcirculation as one prime, possibly causal effector of insulin resistance. To present this novel hypothesis, the specificities of microvascular physiological mechanisms and the limits of interpretations of data according to the measurement techniques used are first thoroughly described. Several chapters deal with experimental and clinical investigations showing the involvement of microcirculation in insulin resistance. This book provides sound support for microcirculation being linked to insulin resistance at least in a bidirectional way. Supportive evidence suggests that microvascular dysfunction may lie upstream of insulin resistance in many of them. While this is still a hypothesis, the authors believe that there is enough data supporting it and hope that this book will stimulate researchers to provide the necessary final proofs.

Micronutrients, which comprise minerals and vitamins, are essential for a variety of biological processes such as growth, immune response, regulation of gene expression and cognitive functions. Micronutrients: The Key to Good Health presents key information about the causes, signs and symptoms of micronutrient deficiencies along with remedial dietary measures. The book also provides authentic knowledge of the nature, structure and metabolic functions of vitamins and essential minerals in a reader-friendly manner. The aim of the book is to provide comprehensive knowledge about micronutrients and their role in a balanced diet for maintaining personal health.

Key features:

- Covers the basics of nutrition and the importance of micronutrients in health over 5 reader-friendly chapters

- Covers metabolic functions of micronutrients - Covers the development of micronutrient rich food products

- Includes information about micronutrient deficiencies with remedial dietary measures in terms of ready-to-eat food supplements in a precise manner

- Includes information about phytochemical nutrients, prebiotics and postbiotics

- Informs the reader about myths on micronutrients

- Includes several informative illustrations, tables and appendices on daily nutrient requirements, diet assessment and composition and much more,

This book serves as a ready reference for the health science students, public health workers, nutrition professionals, and health-conscious readers.

This volume presents information about protocols for micropropagation of more than 40 species of medicinal plants. The contents combine knowledge about the scientific principles of micropropagation with state of the art updates in tissue culture techniques presented by plant scientists.

The readers will learn about techniques required to grow plants in challenging conditions that aim to reduce the impacts of injudicious harvesting, deforestation, climate change, pollution, urbanization and other factors that limit the ability to meet current demand. General topics such as biotization and pharmaceutical investigation are also included to guide readers about the significance of these plants in research and development for new medicines.

The book provides protocols for micropropagation of important medicinal plants like Rauvolfia serpentina, Catharanthus roseus, Withania somnifera, Tylophora indica, Bacopa monnieri, Aloe vera, Phyllanthus amarus, Allium sativum, Moringa oleifera, Operculina turpethum, Glycyrrhiza glabra, Pterocarpus marsupium, Vetiver grass, Ruta graveolens, Tinospora cordifolia, Kaempferia, Hedychium, Decalepis hamiltonii, Saraca asoca, Wrightia tinctoria, Wrightia arborea, Artemisia absinthium, Aegle marmelos, Atropa acuminata, Atropa belladonna, Alpinia species, Hedychium species, and Cissus species.

This book is a handy reference for medicinal chemists, horticulturists and pharmacists who want to learn about the growth and conservation of important medicinal herbs and plants.

During the last two decades microsurgery has progressively taken the place of macrosurgery since it largely improves the experimental models in liver research. This is a concise but comprehensive book focusing on key issues in microsurgical techniques for liver research. The book has been written for medical, biological, veterinary and pharmaceutical researchers and advanced students who wish to develop experimental models of liver diseases by using microsurgery. The book is organized in twelve chapters in which the basic and applied aspects of experimental liver surgery are included. Many illustrations are given to reproduce each microtechnique which should particularly useful to the readers.

Mind Maps in Clinical Biochemistry is an essential test preparation guide aimed specifically at students studying clinical biochemistry as part of their medical, nursing, or biomedical science courses and for candidates preparing for postgraduate entrance and board examinations. The book presents a series of comprehensive case- based learning modules designed to address key teaching points in clinical biochemistry in the context of real clinical experience. Students can begin to understand routine clinical cases by reading biochemical results in the context of a clinical history, examination findings and other diagnostic information. The content also equips readers with the information to propose a differential diagnosis, a treatment plan and a prognosis at later stages.

Key Features

· Concept maps for basic and applied clinical biochemistry

· Structured outline for clinical cases including history with lab findings, clinical correlations and clinical evaluation

· Answers and explanations to facilitate learning

· References for further reading

· OSPE questions for self-assessment and exam preparation

Mind Maps in Clinical Chemistry presents information about clinical laboratory techniques for junior healthcare professionals, medical residents and students. Each chapter enables readers to suggest, arrange and interpret clinical chemistry tests effectively with the objective of enhancing clinical care.

Chapters of this part cover a range of topics focused on biochemical analysis including tumor detection, special topics in clinical biochemistry, the clinical chemistry of diseases, lab instrumentation and reference ranges of diseases.

Key Features

i. Topic-based presentation through 31 chapters in 6 sections

ii. Coverage of practical and theoretical knowledge

iii. Lucid and integrated presentation of concepts

iv. Wide range of topics covered including tumor detection, special topics in clinical biochemistry, the clinical chemistry of diseases, lab instrumentation, and reference ranges in medical diagnosis

v. Packed with practical lab testing information

Mind Maps in Clinical Chemistry is an ideal textbook for quick and easy learning of clinical laboratory knowledge for undergraduate and graduate students as well as teachers instructing courses at these levels.

Mitochondria are multifunctional organelles that actively participate in the immune-inflammatory response in various pathologies. This volume updates readers on knowledge about mitochondria function. The editors have compiled six chapters about inflammation in its broadest sense, with contributions from active groups of cell biologists, infectologists and pathologists.

The chapters in this volume focus on research related to five notable diseases:

(1) two diseases (one bacterial and one viral) in which the exacerbation of the inflammatory response can lead to neuropathies: leprosy (one of the oldest diseases in the world) and Zika fever (a disease relatively new in Brazil)

(2) three diseases (two bacterial and one viral) in which the exacerbation of the inflammatory response can lead to irreversible lung damage that can cause rapid death: tuberculosis, pneumonia and the most recent global disease, COVID- 19.

New information about mitochondrial biology is presented, such as the effect of aerobic physical exercise as a stimulator for mitochondria multiplication, and the role of mitochondrial damage in inducing immune-inflammatory responses to pathogens. The contents shed light on mitochondrial biochemical pathways that could serve as potential therapeutic targets.

This is an important reference for scholars (cell biologists, microbiologists) in universities, hospitals and scientific research centers working on biological and biomedical problems, and for health professionals involved in infection control.

This book focuses on recent developments in integrating AI, machine learning methods, medical image processing, advanced network security, and advanced antenna design techniques to implement practical Mobile Health (M-Health) systems. The editors bring together researchers and practitioners who address several developments in the field of M-Health. Chapters highlight intelligent healthcare IoT and Machine Learning based systems for personalized healthcare delivery and remote monitoring applications. The contents also explain medical applications of computing technologies such as Wireless Body Area Networks (WBANs), wearable sensors, multi-factor authentication, and cloud computing. The book is intended as a handy resource for undergraduate and graduate biomedical engineering students and mobile technology researchers who want to know about the recent trends in mobile health technology.

This eBook covers the application of high-throughput R&D to both fundamental and applied catalysis including catalyst synthesis, characterization, and testing in various reactor types. Chapters include topics such as applications ranging from optimizations of established industrial catalysts to the discovery of innovative new materials, examples of the development of innovative parallel characterization methods, and cases of real catalyst testing in small scale reactor systems. Readers will also find chapters that cover commodity chemicals produced using continuous gas phase processes as well as fine chemicals produced in liquid phase batch reactors. The potential of industrial chemicals production from biorenewable feedstocks is also presented. The steadily improving high throughput workflows are today being applied to relevant reactions and targets such as hydrotreating, Deacon oxidation, Fischer-Tropsch, propane dehydrogenation, C4 oxidation, methane coupling, exhaust gas catalysis, bio-based Nylon, fuel cells and vitamins. The topics presented in this eBook have been contributed by researchers from academia as well as industry, making this eBook a well-balanced reference, which could be of particular interest to professional, industrial or service R&D labs.

His text book serves as a guide for readers learning about the technical design of intelligent instruments, that is, instruments designed to collect information about the performance of other electronic devices and systems. The book introduces the readers to the concept of intelligent instrumentation and guides them on more advanced aspects of the subject including signal detection and analysis, data processing, performance analysis and data communication. Practical examples are also provided in the latter half of the book to blend the theoretical concepts with applied knowledge for the benefit of the reader.

Key features:

- Features 10 chapters covering key topics related to intelligent instrument design and operation

- Provides theoretical knowledge of fundamental concepts

- Provides practical examples of working instrument models (online equipment monitoring system and a mobile robot)

- Provides notes on the use of packages such as MATLAB, ARGUINO and Proteus to develop intelligent instruments

- Presents information in a simple, easy-to-understand format which is reader friendly

- Presents handy chapter notes and references for the reader

Modern Intelligent Instruments - Theory and Application is a useful textbook for engineering students and technical apprentices learning about instrumentation and PCB design and testing.

This comprehensive book covers spectral analysis theory for radio signals and innovative devices designed for filtering electromagnetic waves across diverse frequency ranges. The book features 14 chapters that explain the working of devices utilizing surface and bulk acoustic waves. The chapters provide insights into acousto-optical and acousto-electronic Fourier processors' design principles, description methods, and characteristics. The inclusion of algorithms for multi-channel frequency discriminators enhances the precision of radio signal frequency measurements, ensuring stability in tracking frequency meters amidst intense interference. The book also includes mathematical modeling and experimental studies of waveguide microwave filters and X-band multiplexers, specifically tailored for non-pressurized radio electronic equipment in space communication systems. Notably, the book introduces readers to a compelling alternative to conventional filters: 2-D periodic structures in the form of thin perforated metal meshes that offer compact solutions for millimeter and sub-millimeter wave systems. A significant portion of the book is dedicated to the development of highly selective microstrip filters, incorporating complex topological structures with limited resonators and numerous couplings. This approach allows for the formation of numerous attenuation poles at finite frequencies, facilitating the achievement of high electrical parameters and compact filter sizes. Engineers and scientists specializing in communication systems design and analog Fourier processors will find a wealth of well-established and original solutions within this book.

Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occurs in the nucleus basalis, whereas in Parkinson disease, neurons in the substantia nigra die. The most severely affected neurons in Huntington disease are striatal medium spiny neurons. The neuronal populations that are lost in neurodegenerative diseases modulate functions such as controlling movements, processing sensory information, memory, and making decisions. Although, the molecular mechanism of neurodegeneration remains unknown, but excitotoxicity, inflammation, and oxidative stress may contribute to neural cell demise independently or synergistically. The purpose of this E-book is to present readers with cutting edge and comprehensive information on molecular aspects of neurodegenerative diseases and neuroprotection in a manner that is useful not only to students and teachers, but also to researchers and physicians.

This volume of Frontiers in Heart Failure comprehensively covers the gap between clinical management of heart failure and advanced molecular imaging techniques (SPECT, PET, MRI etc.). These techniques provide valuable evidence to cardiologists for the evaluation and follow-up of heart failure patients. It brings forth established research data regarding the pathophysiology, clinical presentations and therapy of heart failure, in a balance between clinical items and molecular imaging modalities. Readers will also find additional chapters on hybrid cardiovascular imaging techniques as well as guidelines on imaging artifacts and radiation protection. This volume is a useful resource for radiologists, cardiologists, cardiac care nurses and medical physicists.

Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecular targets and rational drug design on this molecular basis should help in discovering early cancer biomarkers as well as novel therapeutic drugs.

This book describes various cancer topics on a molecular level and integrates information on the relationship between causes of cancer, cancer cell biology, metastasis, cancer prevention and drug design. This book should prove to be an extraordinary reference text for students, physicians and oncologists.

Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early-stage diagnosis.

Molecular Targets and Cancer presents information about cancer diagnosis and therapy in a simple way. It covers several aspects of the topic with updated information on par with medical board levels. The book features contributions from experts and includes an overview of cancer from basic biology and pathology, classifications, surveillance, prevention, diagnosis, types of cancer, treatment and prognosis.

The second part of this book discusses specialized topics in clinical oncology which include the pathophysiology of various types of cancer, cancer screening, different types of cancer surgery, cancer stem cell-targeted immunotherapy, nanotechnology for precision medicine applications in cancer and cancer surveillance.

This comprehensive guide is a valuable resource for oncologists, researchers, and all medical professionals who work in cancer care and research.

Molecular and Physiological Insights into Plant Stress Tolerance and Applications in Agriculture is an edited volume that presents research on plant stress responses at both molecular and physiological levels. Key Features: - Emphasizes the morphological and physiological reactions of plants and the underlying molecular mechanisms when faced with stress from environmental or pathogenic factors. - Explores microbial dynamics within the plant rhizosphere and the application of plant growth-promoting bacteria as biofertilizers and endophytes as biocontrol agents to enhance crop growth and productivity for sustainable agriculture. - Systematically summarizes molecular mechanisms in plant stress tolerance and discusses the current applications of biotechnology, nanotechnology, and precision breeding to obtain stress-tolerant crops, contributing to climate-smart agriculture and global food security. - Includes contributions and references from multidisciplinary experts in plant stress physiology, plant molecular biology, plant biotechnology, agronomy, agriculture, nanotechnology, and environmental science. The content of the book is aimed at addressing UN SDG goals 2, 12, and 15 to achieve zero hunger and responsible consumption and production, and to sustainable use of terrestrial ecosystems, respectively. This comprehensive resource is suitable for researchers, students, teachers, agriculturists, and readers in plant science, and allied disciplines.

Marine ecosystems offer several benefits to human communities. To make sustainable use of these benefits, it is necessary to elucidate and conserve marine ecology, and strive to maintain a sustainable natural resource management program. For this reason, understanding the diversity and behavior of both macro-ecosystems and micro-ecosystems are crucial.

Monitoring Artificial Materials and Microbes in Marine Ecosystems explores microbial roles and their interaction with artificial materials in marine environments. After starting with simple topics for beginners, chapters explore methods to detect microorganisms in marine ecosystems and interactions of marine organisms with artificial materials. The sequential progression into advanced topics makes it easier to understand how to solve the reduction in marine-ecosystem viability caused by adverse events. Readers are provided with useful information for rehabilitating marine environments to make them sustainable for communities.

Topics are covered in 3 parts:

Part 1 is an introductory guide to marine ecosystems and environmental monitoring assessment. Readers are introduced to coral reef ecosystems, algal blooms and the role of environmental monitoring services in maintaining and restoring the quality of marine environments. This is followed by examples of sustainable marine environment assessment.

Part 2 provides information about methods to detect microorganisms (viruses and bacteria) and evaluate marine environments. This includes sample enrichment methods, electrochemical analysis, and single-cell imaging techniques. The highly sensitive and specific techniques presented in the book, are applicable in a wide variety of situations.

Part 3 is dedicated to interactions between artificial metallic materials and microorganisms in marine environments. Chapters in this section share results from several experiments conducted to separate microorganisms and biofilms from such environments.

This book is intended primarily for marine ecologists, microbiologists, environmental engineers, and engineers associated with industrial projects. This book is also useful as a text for undergraduate and graduate-level courses in marine biology, ecology, and microbiology.

Morphea and Related Disorders is a comprehensive reference on morphea. The book covers the subject in 20 chapters. The book starts with a detailed introduction and history of the morphea and its various classifications systems. Next, the book progresses into epidemiology, predisposing factors and pathogenic mechanisms, followed by histopathology for morphea diagnosis and a detailed review of clinical presentations.

Subsequent chapters cover associated diseases and extracutaneous manifestations, medical investigations, treatment guidelines and special topics (Idiopathic atrophoderma of Pasini and Pierini, Linear atrophoderma of Moulin, Parry-Romberg syndrome, Lichen sclerosus, pediatric morphea and eosinophilic fasciitis).

Key features:

-he most detailed reference book on morphea

-Easy and simple language for readers

-Chapter synopsis at the beginning of each chapter

-Learning points at the end of the chapter

-More than 100 high resolution colored photographs

-Information boxes and tables to enhance readability.

-Covers basic knowledge on morphea, including pathogenesis, clinical presentations, and classification

-Includes guidelines for professionals

-Includes chapters on special topics for advanced readers

Morphea and Related Disorders is the definitive reference book for medical students, residents, instructors, and physicians.

Mucosal Vaccine Delivery Systems: The Future of Immunization – Part I presents a pioneering exploration into the realm of mucosal vaccination, covering innovative delivery platforms, immunological mechanisms, and their diverse applications in human and veterinary medicine. This comprehensive volume examines the regulatory, economic, and technological landscapes shaping mucosal vaccine development, highlighting their pivotal role in combating infectious diseases, chronic ailments, and advancing cancer immunotherapy.

Key Features:

- Detailed insights into nasal, oral, pulmonary, gastrointestinal, and urogenital vaccination.

- Analysis of mucosal vaccines in pediatric and elderly healthcare.

- Exploration of adjuvants, bioprocessing challenges, and commercialization trends.

- Contributions from leading researchers in the field.

Multiple drug resistance among bacteria has become a global issue with a considerable impact on the mortality associated with infectious diseases. This book is a detailed compilation of available knowledge on the surveillance and mechanisms of antibiotic resistance in various countries throughout the world. Readers will be updated on current information on the understanding of mechanisms involved in drug resistance and the geographical distribution of resistance determinant markers. This volume should be a useful guide for microbiologists and clinicians interested in designing antimicrobial therapies tailored for patients in specific geographical regions.

Multi-Objective Optimization in Theory and Practice is a traditional two-part approach to solving multi-objective optimization (MOO) problems namely the use of classical methods and evolutionary algorithms.

This first book is devoted to classical methods including the extended simplex method by Zeleny and preference-based techniques. This part covers three main topics through nine chapters. The first topic focuses on the design of such MOO problems, their complexities including nonlinearities and uncertainties, and optimality theory. The second topic introduces the founding solving methods including the extended simplex method to linear MOO problems and weighting objective methods. The third topic deals with particular structures of MOO problems, such as mixed-integer programming, hierarchical programming, fuzzy logic programming, and bimatrix games.

Multi-Objective Optimization in Theory and Practice is a user-friendly book with detailed, illustrated calculations, examples, test functions, and small-size applications in Mathematica® (among other mathematical packages) and from scholarly literature. It is an essential handbook for students and teachers involved in advanced optimization courses in engineering, information science, and mathematics degree programs.

The surge of multicore processors coming into the market and on users’ desktops has made parallel computing the focus of attention once again. This time, however, it is led by the industry, which ensures that multicore computing is here to stay. Nevertheless, there is still so much research work to be done in multicore hardware-software designs before consumer applications can leverage the benefits of this new paradigm. This ebook is being put forward as a platform for immediate collection of state-of-the-art technologies in both hardware and software designs for multicore computing. With the burgeoning prevalence of multicore processors in embedded systems, real-time systems, multimedia systems, bioinformatics systems, network systems, to list a few, this ebook attempts to cover the design and verification issues related to different application domains as a singular source of reference to the state-of-the-art techniques in multicore processor design and software programming that covers multiple application domains. This ebook will be of immense help to system and software engineers, including both experts and non-experts in parallel computing.

Multidisciplinary Interventions for People with Diverse Needs is a book written from an interdisciplinary perspective with the objective of helping readers to understand the problems faced by people with special needs.

Key Features:

- provides an updated theoretical and contextual foundation of medical issues

- provides information about the meaning, evaluation and intervention of the problems related to a variety of debilitating diseases and disability conditions (dementia, language disorders, diabetes, alterations of consciousness, celiac disease and disability in general)

- contains an accessible, well written, didactic text which is useful to both students and working professionals

The book equips the reader with information about different approaches to medical and social issues that arise when dealing with persons who are experiencing some degree of disability. For teachers and working professionals, the handbook serves as a guide for teaching, for the development of the structure of training courses, for the design of evaluation models and intervention of the topics addressed in the book.

The combination of information about the professional and human aspects of special needs education makes this book a useful reference for pedagogues, psychologists, students, teachers and professionals involved in social science, healthcare, and sports medicine, among other fields.

Affective computing is an emerging field situated at the intersection of artificial intelligence and behavioral science. Affective computing refers to studying and developing systems that recognize, interpret, process, and simulate human emotions. It has recently seen significant advances from exploratory studies to real-world applications.

Multimodal Affective Computing offers readers a concise overview of the state-of-the-art and emerging themes in affective computing, including a comprehensive review of the existing approaches in applied affective computing systems and social signal processing. It covers affective facial expression and recognition, affective body expression and recognition, affective speech processing, affective text, and dialogue processing, recognizing affect using physiological measures, computational models of emotion and theoretical foundations, and affective sound and music processing.

This book identifies future directions for the field and summarizes a set of guidelines for developing next-generation affective computing systems that are effective, safe, and human-centered.The book is an informative resource for academicians, professionals, researchers, and students at engineering and medical institutions working in the areas of applied affective computing, sentiment analysis, and emotion recognition.

This textbook provides a quick and easy understanding of multistage interconnection networks (MINs) for engineers. The book contents focus on the design, performance metrics, and evaluation of these networks which are crucial in modern computer architecture. The contents equip engineering students, apprentices and professionals with in-depth knowledge and analysis of MINS, enabling them to build complex computer architectures for efficient data communications and cost effective solutions for circuit design. The book starts with an introduction to MINS and subsequently progresses to the evaluation of a range of MINS (SEN, Gamma-Minus, FTSN, FTGN, SEGIN). Key highlights of the book include: & Easy to understand notes on design, reliability and fault tolerance & Covers a wide range of MIN types with notes on design variants & Supplementary information aiding comprehension of the main content. & A curated list of references for further exploration and deeper understanding.

Fungi are extremely versatile microorganisms as a biotechnology tool having the advantage of being relatively easy to grow, thus making them suitable for large scale production. Fungi have been successfully employed for biotransformations ranging from food manufacturing to drug design. Mycofactories comprise a substantial share of significant current research in the area of fungal biotechnology, and constitutes an effort to compile high level research in this domain. Topics include applications of fungi as a main source for the production of enzymes, manufacture of food derivatives, pigments and additives, and applications in bioremediation.

This volume presents an illuminating analysis of the ways in which normalization processes and practices operate in a welfare state in an age of neoliberalism. This informative book problematizes the meaning of the phrase ‘normalization processes and practices’, that for an Anglophone audience may smack of functionalism. The historical context of the deliberate adoption of normalization processes and practices in Sweden in the post-World War II era was, in the first instance, an expression of the inclusivity designed to decrease inequalities and to achieve social justice. However all the contributors to this volume, show very clearly how notions of normalcy, of normalization, in a neoliberal time operate not only to create an integrating and equalizing context but also, and much more critically, to exclude certain groups of people, and produce a structural inequality that in recent years has been discussed under the term of ‘utanförskap’ or outsiderhood.

Critiquing these interventions, the contributors to this volume show how diverse groups of people - immigrants, families considered 'at risk' by social services, pregnant women, young girls - are variously the objects of context-specific normalization processes and practices that make any resistance to such interventions difficult, if not impossible. What people 'normally do', cloaks that 'normal doing' with a fog of invisibilization that suffocates any form of protest. Normalization thus takes on specific forms of repression in particular circumstances, for instance through the ethnocentric imposition of norms of behaviour on migrants where that ethnocentricity is neither made evident nor acknowledged. This system of normalization also operates in schools, resulting in the reproduction of inequalities and discrimination from an early age. In such normalization processes 'the normal' or 'the usual' becomes a means for reinterpreting structural inequalities in terms of individual choice, and for displacing the responsibilities for change onto those positioned as outsiders. The individual chapters highlight how the operations of normalizing processes work to obscure their functioning, thus making any critique of both the underlying assumptions and their operationalization almost impossible.

This textbook provides an overview of next-generation Field-Effect Transistor (FET) technologies at the intersection of nanoelectronics, device miniaturization, and advanced applications. With a special emphasis on the evolution of semiconductor engineering, the book examines the shift from conventional CMOS to emerging FET architectures aimed at extending Moore ' s Law.

Across 18 chapters, the book explores Tunnel FETs (TFETs), carbon-based FETs, and 2D-material transistors, with discussions on performance, scalability, and reliability. It features detailed analyses of advanced device structures such as HJ-DGV-TFETs, dual-pocket step-channel TFETs, and AlGaN/GaN HEMTs, as well as their roles in memory, photonics, and biomedical systems. The use of nanomaterials in biosensor integration and digital circuit design is also a key theme.

Key features:

-Traces technological transitions from CMOS to novel FETs

-Examines nanoengineered device architectures and materials

-Investigates applications in optoelectronics, memory, and biosensing

-Analyzes simulation approaches for performance optimization

-Highlights interdisciplinary innovations across electronics and healthcare.

Nanobiotechnology is the application of nanotechnology in biological fields. Nanobiotechnology is a multidisciplinary field that currently engages researchers in conventional as well as advanced avenues of engineering and natural sciences.The recent developments in nanobiotechnology have impacted various socio-economic sectors, including medical, agriculture, food, textile, and other industries. Although the integration of nanomaterials with biology has led to the development of diagnostic devices, contrast agents, analytical tools, therapy, and drug-delivery vehicles, bionanotechnology research is still in its infancy. The full potential of developments in this field have yet to be realized.

This book discusses various nano-engineered materials or nanocarriers that are used in different situations. It presents 8 chapters that cover the application of nanobiomaterials in environmental remediation, nanofertilisers, nanobiotics against antimicrobial resistance, nanobiosensors in pathogen detection, and nanotoxicity assessments. Each chapter is structured into easy-to-read sections that explain fundamental and applied concepts of nanobiomaterials. Readers will gain a current view of the biotechnological application of modern nanomaterials and nanoparticles. The book is intended to be a primer for students and researchers in agriculture, biotechnology, and biomedical engineering courses.

This reference reviews the reported literature on new approaches of nanocomposite material preparation and their applications in the development of physical, chemical, electrochemical, biological, fluorescence and colorimetric sensors. Sensor nanomaterials have been extensively used to amplify signals in the detection of a range of chemicals including toxic gases, biochemical nutrients, ions, explosives, pesticides and drugs to name a few. 14 chapter contributions highlight state-of-the-art sensors in recent years by outlining the synthesis, role and progress of nanocomposite materials in fabricating flexible and multifunctional sensing platforms in sensor technologies.

Chapters first introduce the reader to nanocomposite materials and their role in making a wide array of sensors including metal-organic, graphene-based and polymeric sensors. The chapters then progress into applications of sensors for the detection of chemicals such as blood glucose, heavy metal and other toxic ions, hydrazine, humidity and explosive. Each chapter explains the required materials for electrodes and material components for a specific sensor platform with additional information about sample collection, threshold values and perspectives where appropriate.

The book is intended as a compilation of knowledge for designing novel nanocomposite materials to be used as sensing platforms in sensor technologies. It serves as an informative resource for a broad range of readers including graduates and post-graduates, Ph. D. scholars, faculty members and professionals working in the area of material science, the healthcare industry, biological sciences, medical sciences, and environmental sciences.

Nanoelectronics Devices: Design, Materials, and Applications provides information about the progress of nanomaterial and nanoelectronic devices and their applications in diverse fields (including semiconductor electronics, biomedical engineering, energy production and agriculture). The book is divided into two parts. The editors have included a blend of basic and advanced information with references to current research. The book is intended as an update for researchers and industry professionals in the field of electronics and nanotechnology. It can also serve as a reference book for students taking advanced courses in electronics and technology. The editors have included MCQs for evaluating the readers' understanding of the topics covered in the book.

Topics covered in Part 1 include basic knowledge on nanoelectronics with examples of testing different device parameters.

- The present, past, and future of nanoelectronics,

- An introduction to Nanoelectronics and applicability of Moore's law

- Transport of charge carrier, electrode, and measurement of device parameters

- Fermi level adjustment in junction less transistor,

- Non-polar devices and their simulation

- The negative capacitance in MOSFET devices

- Effect of electrode in the device operation

- Second and Sixth group semiconductors,

- FinFET principal and future, Electronics and optics integration for fast processing and data communication

- Batteryless photo detectors

- Solar cell fabrication and applications

- Van der Waals assembled nanomaterials

Nanoscience is a multidisciplinary area of science which enables researchers to create tools that help in understanding the mechanisms related to the interactions between nanomaterials and biomolecules (nanotechnology). Nanomaterials represent nanotechnology products. These products have an enormous impact on technical industries and the quality of human life. Nanomaterials directly or indirectly have to interact with biosystems. It is, therefore, essential to understand the beneficial and harmful interactions of nanomaterials with and within a biosystem, especially with reference to humans.

This book provides primary and advanced information concerning the interactions between nanomaterials and the components of a typical biosystem to readers. Chapters in the book cover, in a topic-based approach, the many facets of nanomolecular interactions with biological molecules and systems that influence their behavior, bioavailability and biocompatibility (including nucleic acids, cell membranes, tissues, enzymes and antibodies). A note on the applications of nanomaterials is also presented in the conclusion of the book to illustrate the usefulness of this class of materials.

The contents of the book will benefit students, researchers, and technicians involved in the fields of biological sciences, such as cell biology, medicine, molecular biology, food technology, cosmetology, pharmacology, biotechnology, and environmental sciences. The book also provides information for the material science personnel, enabling them to understand the basics of target-oriented nanomaterials design for specific objectives.

Nanotechnology is a diverse science that has brought about new applications in fields such as colloidal science, device physics and supra molecular chemistry.

Environmental pollution treatment by nanomaterials is an emerging application of nanotechnology. It is gaining importance because of the increased environmental challenges due to the impact of modern industrial activities. Industrial activity involves the production and use of various toxic organic and inorganic chemicals which pollute nearby water streams, indirectly influencing aquatic and human life. Thus, there is a need to protect the environment through the development of new technologies and by enacting awareness drives for environmental sustainability. This volume summarizes cutting-edge research on nanomaterial utilization for environmental challenges.

Chapters introduce readers to the concepts of environmental protection, sustainability and monitoring. Readers will also learn about technologies used for keeping the environment safer, including ion exchangers, metallic oxide complexes, nanocomposite materials, porous membranes and nanocatalysts.

This volume is intended to be an introductory reference for students and researchers undertaking advanced courses in materials science, environmental science and engineering, giving readers a glimpse into the fascinating world of nanotechnology.

Nanomaterials in Glioblastoma Research, Diagnosis, and Therapy offers a comprehensive exploration of how nanotechnology is revolutionizing the fight against glioblastoma (GBM), one of the deadliest and most treatment-resistant brain cancers. The book covers the molecular and epigenetic mechanisms underlying GBM, laying the foundation for innovative strategies in diagnosis and therapy. It highlights cutting-edge advances, including nanomaterial-based biosensors for early diagnosis, biomaterials to enhance immunotherapy, and novel therapeutic approaches like gold nanoparticles, cold plasma, and combinational nanomedicine. The book also addresses critical challenges such as overcoming the blood-brain barrier through oral delivery nanostructures and provides future perspectives on clinical applications.

Key Features:

- Insights into GBM genetics, epigenetics, and molecular pathways.

- Applications of nanomaterials in drug delivery, imaging, and immunotherapy.

- Detailed coverage of advanced diagnostics and therapeutic strategies.

- Future directions and challenges in nanotechnology-based GBM treatment.

This book explains various methods needed to overcome the challenges faced during environmental remediation with a focus on nanotechnology. The book comprises ten edited chapters that aim to inform and educate readers about recent technologies that are beneficial for pollution control.

Starting with an introduction to environmental remediation, the book covers innovative nanomaterials including spinel nanoferrites, carbonaceous quantum dots, carbon nanotubes and nanobioadsorbents. In addition to highlighting the environmental benefits of these materials, the book includes chapters on the potential of nanotechnology for harnessing the environment to generate energy through nanogenerators and piezoelectric energy harvesting devices.

Key features of the book include notes on fundamental issues and challenges regarding environmental remediation, easy to read content with pictorial illustrations and scholarly references for each chapter. The book is an informative resource for students and academicians in science, technology and environmental science discipline.

The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release.

In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies.

Part II covers the following topics:

· Solid lipid nanoparticles and nanostructured lipid carriers

· Silica based nanomaterials

· Hydrogels

· Metallic nanoparticles

· Computational and experimental binding interactions of drug and β-cyclodextrin

· Clinical milestones in nanotherapeutics

· Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers

The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Frontiers in Nanomedicine offers an up-to-date understanding of nanomaterials to readers having clinical or biomolecular research interests. Scientists, both aspiring and experienced, will find, in each volume, a comprehensive overview of current molecular strategies for using nanoscale materials in medicine.

Nanomedicine and Neurosciences: Advantages, Limitations and Safety Aspects presents different aspects of nanomedicine applied to neuroscience for the diagnosis of disease and the role of nanoparticles in targeted drug delivery systems for neurodegenerative disorders. Topics covered in this volume cover the physiology of neurodegeneration, targeted therapies for Alzheimer's disease and Parkinson's disease, blood brain barrier drug delivery systems, in vivo studies of drug nanoconjugates, nanomedicine safety, and more.

This book explains key concepts and applications of nanotechnology in clinical medicine and pharmacology. The chapters have been contributed by experts and provide a broad perspective about the current and future developments in pharmacology, toxicology, cell biology, and materials science. The book is divided into 2 main sections. The first section concerns nanobiotechnology for human health including gastrointestinal disease, kidney diseases, pulmonary disorders, reproductive system, COVID-19, and cancer. The second section is devoted to toxicological aspects of nanomaterials which involve toxicological assessments of nanotherapeutics and potential solutions for nanotoxicology. Key Features - Emphasizes the high degree of interdisciplinary research in pharmacology, toxicology and nanoscience - Summarizes the results of theoretical, methodological, and practical studies in different medical subspecialties - includes special topics such as novel nanotoxicology assessment methods and nano vaccines - Includes references for further reading

Burns can cause life-threatening injury and the lengthy hospitalization and rehabilitations required in burn therapy lead to higher healthcare costs. The risk of infection has also been one of the important concerns of burn wound management. The purpose of the burn wound care management is speedy wound healing and epithelization to limit the infection. The topical application of therapeutic agents is quintessential for the longevity of patients having significant burns.

In recent times, research on herbal medicine for burn wound management has been vastly increased because of their safer toxicological profiles in contrast to synthetic medicines. Despite the promising therapeutic potential of herbal medicines in this area, herbal medications have some limitations which include low pharmacological activity, solubility and stability. Nanotechnology-based smart drug delivery approaches which involve the use of small molecules as nanocarriers, however, can help to overcome these biopharmaceutical challenges.

This book provides an overview of plant-mediated metallic nanoparticulate systems and nanophytomedicine based therapeutic treatment modalities for burn wound lesions. Nine chapters deliver updated information about nanomedicines for burn wound therapy. Contributions are written by experts in nanomedicine and phytomedicine and collectively cover the pathophysiology of wound lesions, current and future outlook of nanomedicine based treatments for burn wound lesions, the role of biocompatible nanomaterials in burn wound management, plant-mediated synthesis of metal nanoparticles for treating burn wound sepsis, phytomedicine based nanoformulations and the phyto-informatics models involved in the wound healing process which are used to select appropriate nanotherapeutic agents.

This reference serves as an accessible source of information on the topic of nanomedicine for burn treatments for all healthcare professionals (medical doctors, nurses, students trainees) and researchers in allied fields (pharmacology, phytomedicine) who are interested in this area of medicine.

This book provides a compressive overview of nanotechnology in modern drug discovery for students and researchers. The book starts with the fundamentals of nanotechnology followed by nanomaterials in pharmaceutical drug design, drug delivery applications, regulatory aspects, formulation and nanoparticle biotransformation. It provides a step by step guide through the drug development process while conveying information about the benefits of nanomaterials for therapy. The book concludes with perspective on the future of nanotechnology-based drug discovery, summarizing current knowledge on nanotherapeutics and translational medicine.

Key Features

- Explains the fundamentals of nanotechnology in drug discovery

- Includes up-to-date information on modern nanopharmaceutical manufacturing, nanomaterials, and nanoparticle-based drug therapy

- Practice questions for learners and a list of references for advanced readers for each chapter

Nanotechnology: A Quick Guide to Materials and Technologies invites readers to explore the cutting-edge world of nanotechnology, offering a comprehensive yet accessible introduction to this rapidly evolving field. The content provides a foundation for understanding the field and details the properties of significant nanomaterials. Readers will also gain insights into innovative processes while receiving a balanced perspective on the social and regulatory aspects of nanotechnology.

Key Features:

Foundational Knowledge: Begins with an overview of nanotechnology, its history, and its key concepts,

Diverse Nanomaterials: Explores various types of nanomaterials, including nanoparticles, nanowires, and carbon-based materials like graphene, detailing their properties and potential applications.

Advanced Applications: Explores the real-world uses of nanotechnology across multiple sectors, such as medicine, electronics, energy, and environmental science, demonstrating its transformative impact.

Fabrication and Characterization: Covers techniques for creating and analyzing nanomaterials, offering insights into the processes that drive innovation in the field.

Ethical and Societal Considerations: Discusses the broader implications of nanotechnology, including ethical, societal, and regulatory aspects

Ideal for students, educators, researchers, and industry professionals, this guide serves as an informative resource for anyone looking to deepen their understanding of nanotechnology.

Advances in technology have enabled medicinal chemists to discover and formulate several highly specific, biocompatible, and non-toxic therapeutic agents for clinical applications. Nanotechnology has achieved significant progress in the last few decades and is crucial in every field of science and technology. Nanotechnology-based pharmaceuticals offer multifaceted and alternative methodologies in comparison to the limitations of many conventional clinical therapies. Expertise in designing and developing nanoformulations has helped in targeted drug delivery. Recently, the use of innovative therapeutic agents, particularly in nanomedicine, has accounted for a significant portion of the global pharmaceutical market and is predicted to continue to grow rapidly in the near future. Nanotherapeutic Strategies and New Pharmaceuticals is an accessible multi-part reference which informs the reader about several new techniques based on nanotechnology. The chapters explain relevant topics in detail. The book is designed to encourage and help undergraduate, graduate and post-graduate students in the field of nanotherapeutics, pharmaceuticals and bio-organic chemistry through the use of didactic language and simple illustrations. Part 2 of this book covers the potential of nanotherapeutics and natural therapies for treating neurological diseases, targeting ion channels, signal transduction therapy, gene therapy of single gene mutation diseases and for nanoformulations for special purposes such as wound healing and stimuli-responsive drug delivery. The book also features a chapter that summarizes the types of nanoparticles tailored for specific molecular targets that mediate different diseases. The book set serves as a textbook for students in pharmacology and medical biochemistry, as well as a quick reference for researchers on bio-organic chemistry, as well as general readers interested in nanomedicine.

Plants have been widely used to treat diseases, owing to the presence of bioactive compounds (phytochemicals) which play important roles in health promotion and disease prevention. In recent years, advances in chemical extraction techniques, lifestyle and dietary choices for human health have increased the interest in the consumption and study of fruits, vegetables, and foods enriched with bioactive compounds and nutraceuticals. Thousands of dietary phytochemicals, such as flavonoids, phenolic acids, glucosinolates, terpenes and alkaloids, have been identified and categorized further according to a diverse array of biochemical properties. Many of these phytochemicals have been hypothesized to reduce the risk of several pathological conditions which include life threatening diseases such as heart disease and cancer, to name a few.

Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters is a 2 book set which presents a summary of different classes of phytochemicals commonly found in common edible food sources. Each chapter details the general chemical structures of compounds, naturally present in specific fruits, vegetables and grains, their biological importance and mechanisms of action.

The book set is an essential handbook for anyone interested in the natural product chemistry of these common crops.

Part 1 of this set covers details about different fruits (banana, citrus fruits, pears, etc.). Part 2 covers legumes, nuts, seeds and cereals.

In nature lies the solution to restore teeth with minimal damage. In this groundbreaking book, the management of dental challenges is presented from a new perspective. Natural Conservative Dentistry: An Alternative Approach to Solve Restorative Problems provides evidence-based solutions to dental challenges to researchers, practitioners and dental service providers. The main attribute of all these solutions is that they are all derived from natural ingredients. Natural ingredients are an effective alternative for dental care and management in contrast to synthetic products that have multiple side effects.

This book fills a knowledge gap on alternative and sustainable solutions derived from nature to respond effectively to dental challenges encountered in dental treatment for the conservation of the tooth. It is a compilation of the work of expert dentists that has been carried out in clinics for the management of dental problems.

Key Features

- Provides an insightful look at the prevention of dental diseases through evidence-based interventions using natural products in 9 referenced chapters

- Contains valuable contributions in restorative dentistry, such as caries prevention, enamel and dentin remineralization, dentin biomodification, dentin desensitization, vital pulp therapy, antioxidants, and tooth bleaching

- Provides an update on the current status of different ingredients used in oral health care products developed for commercial markets

- Includes notes on pathophysiology and diagnosis on specific conditions and sources of natural ingredients

The book is a valuable reference for trainees and professionals who want to enhance their restorative dentistry practice in the clinic.

Natural Immunomodulators: Promising Therapy for Disease Management discusses the use of natural immunomodulators as a promising therapy for managing various diseases. The book begins with an introduction to the immune system and the ways in which it can be modulated. This is followed by a discussion on the various diseases and disorders associated with the immune system, including autoimmune disorders, allergies, and immune deficiency conditions. The natural sources of immunomodulators, including plants, herbs, and other natural substances is also explained along with the importance of standardizing natural immunomodulator drugs, including the methods used to ensure their quality and consistency. The book also delves into the chemistry and analytical techniques used to study immunomodulators, clinical and pre-clinical bioassays. The next couple of chapters focus on the use of natural immunomodulators in cancer, the therapy of cancer and infectious diseases. Drug delivery and the strategy and regulatory perspective for natural immunomodulators. The final 2 chapters round up the contents with information about synthetic immunomodulators and the future perspective for the use of immunomodulators in disease management. Natural Immunomodulators: Promising Therapy for Disease Management is a comprehensive guide to the use of natural immunomodulators as a therapy for various diseases, and is a valuable resource for professionals and students interested in this topic. The book is aimed at health care professionals such as medical doctors, nurses, pharmacists, and life science and nutritionist professionals, as well as students.

Natural Products for Skin Diseases: A Treasure Trove for Dermatologic Therapy is an enlightening journey through the realm of natural remedies for various skin diseases. The editors have compiled information on effective and holistic treatment approaches that can be applied in clinical settings. This book brings diverse range of topics, including skin protection against harmful radiation, natural remedies for burns and wounds, management of skin pigmentation issues, and herbal treatments for scabies. It also explores the potential of natural cosmetics and their future applications, along with the use of natural products and nanoparticles in skin delivery. All chapters are contributed by experts in dermatology and herbal medicine, and are supplemented with scientific references for advanced readers. The book primarily serves as a textbook for students in medicine and dermatologists in training. It also serves as a valuable guide for dermatologists, researchers, and healthcare professionals, revealing the treasure trove of benefits that natural products offer for treating skin diseases.

Rheumatoid arthritis (RA) is the most common inflammatory complication and affects approximately 1 % of the global population. It affects three times more women than men. RA is an autoimmune disorder elicited by exposure of genetic factors from the host to unknown antigens causing arthritogenic complaints. It also includes the activation of lymphocytes as well as CD4+ helper T cells along with the local release of chronic inflammatory mediators and cytokines like tumor necrosis factor (TNF-α) and various cytokines like interleukins (IL) that enormously affect the joints. The available allopathic therapies for RA are not a cure for the complications, and antibody therapy and surgical procedures are expensive.

However, in the present era, researchers and healthcare professionals have moved toward natural medicines obtained from plants and other natural sources. Research-based on developments in phytomedicine has progressed steadily. Evidence has been collected to show the massive therapeutic potential of medicinal plants used in various traditional systems against many pathological complications. Researchers have focused on the therapeutic potential of natural products used for treatment and counteracting various disorders along with their complications having negligible adverse effects.

Natural Products for the Management of Arthritic Disorders compiles current knowledge about the bioactive compounds and herbal formulations useful in the treatment of rheumatoid arthritis. 11 chapters explain the role of natural products in the management of rheumatoid arthritis. Topics have been contributed by experts in medicinal chemistry and rheumatology.

The book first introduces the reader to rheumatoid arthritis before delving into conventional and alternative therapies for the disease. The editors have also included special topics such as the biomarkers for RA, cytokines and anti-inflammatory mediators, and preclinical and clinical studies. The range of topics should provide a comprehensive overview of natural remedies for arthritis and the role of natural products in anti-arthritic drug development.

The information will be useful for many readers including medical and pharmacology students, multidisciplinary research scholars, scientists, pharma/herbal/food industrialists, and policy makers.

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bioactive natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives.

The second volume covers the following topics:

- A review of recent patents and natural products in clinical trials to treat schistosomiasis

- Natural products: the new intervention regimen for metabolic disorders

- Fluorine-containing drugs and drug candidates derived from natural products

- Natural products for the management of cardiovascular diseases

- Implication of natural compounds for the prevention of ocular diseases