Bentham Science Publishers

Natural Feed Additives Used in the Poultry Industry addresses recent information on the use of different natural feed additives in poultry nutrition. Chapters in the book focus on the growth, production, reproduction and health of poultry.

Key Features:

- 15 chapters contributed by more than 30 experts and scientists involved in animal and poultry nutrition, physiology, toxicology, pharmacology, and pathology

- Chapters highlight the significance of a variety of herbal plant extracts and derivatives, cold pressed and essential oils, fruits by-products, immunomodulators, organic acids, probiotics, nanoparticles and their role in poultry industry instead of the growth promoter antibiotics.

- Provides details about the use of antibiotic as growth promoters in poultry and the development of bacterial resistance.

- Provides a holistic approach on how natural feed additives can provide an efficient solution to animal health,

- Covers the main categories of poultry, including broiler chickens, laying hens, quails, geese, ducks, and turkey.

- References in each chapter for further reading

This handbook represents an up-to-date review of the existing knowledge on natural feed additives, both in vitro and in vivo and the basis for future research. The text is useful to students of poultry sciences, nutritionists, scientists, veterinarians, pharmacologists, poultry breeders, and animal husbandry extension workers.

The Natural Products Journal a peer-reviewed journal, aims to publish all the latest and outstanding developments in natural products.
The Natural Products Journal publishes original research articles, full-length/mini-reviews, letters, and guest-edited issues on all aspects of research and development in the field, including isolation, purification, structure elucidation, synthesis, and bioactivity of chemical compounds found in nature. Articles related to recent developments in medicinally important natural products, particularly concerning the structure-activity studies regarding certain diseases, such as inflammation, cancer, tropical diseases, diabetes, cardiovascular diseases, etc., are also covered in this journal.
The Natural Products Journal is an international, peer-reviewed journal on all aspects of natural products, published monthly (print & online) by Bentham Science Publishers.

Natural Products for Treatment of Skin and Soft Tissue Disorders presents a simple and straightforward exploration of the role medicinal plants play in treating a diverse range of skin-related disorders. With contributions from researchers worldwide, this book delves into the pathology of skin conditions such as eczema, superficial mycoses, acne, vitiligo, and skin ulcers, providing effective treatment protocols using natural remedies. It also addresses prevalent disorders like atopic dermatitis and skin infections in developing countries. Finally, the book sheds light on the rising concern of skin cancer and potential natural therapeutic approaches. Readers will be equipped with the knowledge to harness the power of natural medicines in their dermatology practice.

This comprehensive resource serves as a handbook for medical residents, students and dermatologists, offering invaluable insights into the potential of medicinal plants for the treatment of skin and soft tissue disorders.

Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume brings reviews contributed by eminent scientists in the field.

The first volume covers the following topics:

- bioactive compounds from marine invertebrates

- natural product derived drugs for immunological and inflammatory diseases

- clinical trials of curcumin, camptothecin, astaxanthin, and biochanin

- antibacterial and antifungal drugs from natural sources

- natural products as anti-HIV medicines

This volume presents different aspects related to bioactive compounds, starting with their natural state in raw sources, physicochemical characterization and employment in pharmacy and medicine. The volume is divided into three parts. The first part describes the chemicals structure of bioactive compounds from different natural sources such as olive oils, wines, and medicinal plants. Special attention has been given to identifying the bioactive composition within variations of these natural sources (for example, extra virgin, ordinary or lampante olive oils). The second part of the volume presents the principal methods used for detecting, identifying and quantifying bioactive compounds. Emphasis is given to the use of different types of sensors or biosensors, and multisensor systems in combination with analytical techniques. The final part explains the principal methods for protection of bioactive compounds and the implication of bioactive compounds in pharmacy. This volume is a useful guide for novice researchers interested in learning research methods to study bioactive compounds.

Frontiers in Bioactive Compounds brings edited reviews on the analysis and characterization of natural compounds of medicinal interest. Each volume covers useful information on a variety of natural sources as well as analytical techniques. This series is essential reading for analytical and medicinal chemists as well as professionals involved in natural and pharmaceutical product research and development.

Navigating through Technology in Modern Education explores the transformative impact of digital innovation in education. From introducing digital transformation to discussing the benefits and challenges, this book covers crucial topics like e-learning, artificial intelligence, big data, and the Internet of Things in education. With insights into factors for adopting technology and tailored learning experiences, this book equips readers with the knowledge to navigate the evolving landscape of modern education. Whether you're a seasoned educator or a newcomer, this book offers valuable insights into leveraging technology for enhanced learning experiences.

Research on young individuals and childbearing adults being treated for neoplasia has revealed a rising number of requests for treatments aimed to maintain the possibility to conceive. To answer such requests, it is important for medical professionals to consider the necessity to cure the woman, to preserve her fertility, to give information both on the effect of neoplasia and treatments on pregnancy. Patients have to be informed on the possible treatment alternatives that are less aggressive towards the reproductive function, but at the same time, give desirable results in terms of survival.

Neoplasia and Fertility describes the state-of-the-art on fertility preservation in women affected by neoplasia. The 11 book chapters inform the reader with the goal of equipping them with the required information needed to present the condition and to discuss the possibility of conceiving, and how to manage patients after oncologic treatments at different stages of pregnancy.

Key Features

- Informs the reader about the relationship between gynecological cancer and fertility in women through 11 chapters

- Describes a broad range of cancers and relevant treatment options for maintaining fertility

- Explains the role of a 'Fertility Sparing Team' in clinics

- Familiarizes the reader with the ethics behind oncology treatments with reference to female fertility

- Describes fertility issues related to hereditary cancers in women

- Includes references for further reading

The book serves as an informative reference on the subject to medical doctors in the gynecology, obstetrics and midwife specialties, and nurses training the gynecological oncology. It will also be of interest to healthcare administrators involved in fertility and oncology clinics, as well as general practitioners in family medicine.

This book covers novel approaches using networks and oscillations and it will serve as a catalyst for translating these exciting advancements into the clinical arena. This collection of articles aims to accelerate the widespread clinical translation of network approaches by providing practical information accessible to clinicians in neurology and psychiatry - fields that are uniquely poised to implement these developments in clinical treatment of brain diseases. It should be a useful resource for researchers and working professionals in neurological and psychiatric academic centers.

This monograph is a collection of selected articles on the subject of mood disorders such as depression and schizophrenia. It is divided into 3 sections: 1) Research methods in psychopharmacology - which highlights some established experimental techniques to study mood disorders in human and relevant animal models, 2) Pathophysiology of mood disorders – which explains the physiological and pharmacological mechanisms responsible for mood disorders and 3) New strategies for the treatment of mood disorders – a concluding section that provides recent examples on the beneficial effects of pharmacological and non-pharmacological interventions in the relief of mood disorders. The e-book serves as a primer for graduate students and researchers interested in the physiology and treatment of affective psychological disorders.

NBE is the official journal of the Institute of Complex Medical Engineering (ICME). The journal promotes the best interdisciplinary research in neuroscience and biomedical engineering. NBE welcomes contributions in any domain of neural and biomedical engineering ranging in content from practical/clinical applications through experimental science, technological developments to quantitative and/or statistical methodology discussions. NBE publishes the following article types: original articles, research reviews, and book reviews.

The goal of this journal is to establish a new forum for this interdisciplinary field so neuroscientists and biomedical engineers can publish their research works in one periodical. NBE is devoted to bridge the gap between Neuroscience and Biomedical Engineering , and to foster the mutual understanding in both fields.

Typical topics include, but certainly are not limited, to the following:
Neural Technology and Neural Rehabilitation
Neurology and Signal Processing
Biomedical Informatics
Biomechanics and Neural Control
Theoretical and Computational Neuroscience
Imaging Neuroscience

Key Features:

- Original research papers and special issues for topics
- Basic neurosciences, and biomedical engineering technologies
- Existing and potential clinical applications
- Periodic ‘Review Papers’ from world-recognized experts
- International scope
- No page charges
- Rapid publication times
- Free color in electronic version

Increasingly global and online social interactions and financial transactions involve digital data, computing devices and the internet. With cloud computing, remote computing, enterprise mobility and e-commerce on the rise, network security has become a priority. Selecting an appropriate algorithm and policy is a challenge for computer security engineers, as new technologies provide malicious users with opportunities to intrude into computer networks.

New Age Cyber Threat Mitigation for Cloud Computing Networks provides cloud and network engineers answers to cybersecurity challenges. It highlights new options, methodologies and feasible solutions that can be implemented in cloud architecture and IT Infrastructure, thereby securing end users. Chapters cover many topics related to cyber threats in the modern era.

These topics include:

Ransomware and DDoS attacks

Security algorithms

Design and implementation solutions for resilient and fault-tolerant cloud and network services

Security policy

End user data security The book is an essential resource for anyone involved in cloud computing and network security, including learners, professionals and enthusiasts.

New Avenues in Drug Discovery and Bioactive Natural Products is the second volume of the Natural Medicine book series. It is devoted to current research in drug discovery from natural sources. The volume features 13 chapters that cover modern analytical and scientific approaches. The book starts with chapters on advanced analytical and research techniques, such as genomic mining, quality control of herbal drugs, DNA fingerprinting, high-throughput screening, molecular docking and extraction techniques. The contributors provide a summary of challenges for researchers and commercial applications where possible. The book also features chapters dedicated to specific medicinal agents that target a disease (glycosides, SARS-CoV2 spike protein inhibitors, and andrographolides. The collection of important research topics in natural product chemistry aims to help the scholars and researchers in the scientific community that are involved in the extraction and development of new medicines.

Congenital heart diseases are the most common neonatal malformations, ranging from 8 to 15/1000 live births in various communities. Improvement of knowledge in the genetic and etio-pathogenic aspects of these malformations as well as the technical advances of diagnostic and therapeutic tools have brought about a significant improvement in overall long-term patient outcome over the last few decades. This e-book is an update on the most recent genetic, diagnostic and therapeutic aspects of this pediatric cardiology. Specifically, the book explains, in detail, recent acquisitions in the field of interaction between the genome and heart development, advances in diagnostic non-invasive techniques and novel therapeutic applications of the percutaneous and "hybrid" cardiologic/surgical procedures. These developments in diagnostics and therapeutics will be extremely valuable for both pediatric and adult cardiologists treating patients with congenital heart defects.

The monograph is a summary of methods used to study pain receptors and the results obtained in some experiments designed to study the effect of non-opioid analgesics. The molecular mechanisms of nociceptive information control in primary sensory nociceptive neurons are described based on investigations of the membrane signaling cascade (opioid-like receptor → Na+,K+-ATPase → NaV1.8 channel) observed by the authors. Based on this data, the authors conclude that the modulation of NaV1.8 channels responsible for the coding of noxious signals can be carried out due to two novel targeting mechanisms. The first of these is the activation of opioid-like receptors; the second is the activation of Na+/K+-ATPase as a signal transducer. The development of a novel class of analgesics that trigger these mechanisms should lead to a successful solution to the problem of chronic pain relief.

Chapters of the monograph cover the general methods used in studying nociceptive pain (including the patch-clamp method), and the mechanism behind the binding of different ligands to these receptors such gamma-pyrones, gamma-pyridines and cardiotonic steroids.

This monograph is a valuable reference for neuroscientists, pharmacologists and allied researchers studying pain receptors for the development of safe and effective analgesics.

Terraforming is the process of modifying a planet, moon, or other body to a more habitable atmosphere, temperature, or ecology. The idea of terraforming or colonizing other planets has recently become a topic of intense scientific interest and public debate. Geoengineering and terraforming, at their core, have the same goal: to enhance or revive the ability of a specific environment to support human life, society, and industry. New Worlds: Colonizing Planets, Moons and Beyond examines extra-terrestrial colonization plans with a critical eye. The ten chapters of the book provide a detailed review of the demographic and economic reasons behind this space imperative, technical and ecological solutions to improve the settlement of our own planet, enhancements of our current space industry. The book also covers interesting topics such as the terraformation of Mars, the moon, and other planets like Venus, colonizing the outer solar system (and beyond), and the ethical considerations in favor of space expansion. This simple, yet informative treatise is an essential read for anyone interested in the subject of space colonization

Nitrogen containing compounds produced by industrial processes are pollutants which pose a significant environmental and health hazard. There are a number of processes that have been devised for removing nitrogen compounds from wastewater.

This reference book summarizes different denitrification methods for wastewater processing. The book introduces readers to toxic nitrogen compounds responsible for water pollution. This introduction is followed by chapters which explain different nitrogen removal methods including conventional methods, biological methods, food industry wastewater treatment and new approaches towards environmental pollution remediation: Bio Electrochemical Systems (BESs). This book is a handy reference guide for industrial and environmental engineers and students learning about wastewater management and industrial denitrification.

Non-alcoholic fatty liver disease (NAFLD) is a common cause of elevated liver enzymes and chronic liver disease in Western countries. NAFLD is characterized by elevated liver enzymes in the absence of alcohol consumption and secondary causes of liver disease. It is an independent predictor of future risk of cardiovascular diseases, type 2 diabetes and metabolic syndrome (hypertension, abdominal obesity, dyslipidemia, glucose intolerance).

This book is a quick reference guide for medical students and professionals about NAFLD. Readers will find a summary of epidemiology, clinical features, diagnosis, imaging techniques, histopathology, and disease management. The book also presents information about NAFLD linked with hepatocellular carcinoma and guidelines for treating NAFLD in pediatric patients. Each chapter presents information in a simple, structured manner making this text an ideal handbook for supplementing hepatology modules in medical curricula.

Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics:

o Chromatographic assays of solid dosage forms and their drug dissolution studies

o UHPLC method for the estimation of bioactive compounds

o HILIC based LC/MS for metabolite analysis

o In vitro methods for the evaluation of oxidative stress

o Application of vibrational spectroscopy in studies of structural polymorphism of drugs

o Electrochemical sensors based on conductive polymers and carbon nanotubes

o Optical sensor arrays for pharmaceutical and biomedical analyses

o Chemical applications of ionic liquids

o New trends in enantioanalysis of pharmaceutical compounds

Novel Drug Delivery Systems (Part 2) covers the advanced techniques and innovations transforming pharmaceutical sciences, with a focus on enhancing drug efficacy and patient outcomes. This comprehensive guide explores a wide array of delivery methods, including nasopulmonary, transdermal, ocular, nanotechnology-based, implantable, and controlled-release injectables. Each chapter provides an in-depth analysis of these unique delivery routes, presenting both foundational knowledge and the latest technological advancements in the field.

Designed for students, researchers, and professionals in pharmaceuticals and medicine, this book bridges basic concepts with cutting-edge practices, emphasizing the science and impact of controlled drug delivery.

Key Features:

- Detailed exploration of nasopulmonary, transdermal, ocular, and implantable delivery systems

- Insight into nanotechnology's role in drug delivery

- Comprehensive coverage of controlled-release injectables

Numberama: Recreational Number Theory in the School System presents number patterns and mathematical formulas that can be taught to children in schools. The number theories and problems are reinforced by enjoyable games that children can play to enhance their learning in a fun-loving way. Key features of the book include:

• information about a number of well-known number theory problems such as Fibonaccci numbers, triangular numbers, perfect numbers, sums of squares, and Diophantine equations

• organized presentation based on skill level for easy understanding

• all basic mathematical operations for elementary school children

• a range of algebraic formulae for middle school students

• descriptions of positive feedback and testimonials where recreational number theory has been effective in schools and education programs

This book is a useful handbook for elementary and middle-school teachers, students, and parents who will be able to experience the inherent joys brought by teaching number theory to children in a recreational way.

Numerical Machine Learning is a simple textbook on machine learning that bridges the gap between mathematics theory and practice. The book uses numerical examples with small datasets and simple Python codes to provide a complete walkthrough of the underlying mathematical steps of seven commonly used machine learning algorithms and techniques, including linear regression, regularization, logistic regression, decision trees, gradient boosting, Support Vector Machine, and K-means Clustering.

Through a step-by-step exploration of concrete numerical examples, the students (primarily undergraduate and graduate students studying machine learning) can develop a well-rounded understanding of these algorithms, gain an in-depth knowledge of how the mathematics relates to the implementation and performance of the algorithms, and be better equipped to apply them to practical problems.

Key features

- Provides a concise introduction to numerical concepts in machine learning in simple terms

- Explains the 7 basic mathematical techniques used in machine learning problems, with over 60 illustrations and tables

- Focuses on numerical examples while using small datasets for easy learning

- Includes simple Python codes

- Includes bibliographic references for advanced reading The text is essential for college and university-level students who are required to understand the fundamentals of machine learning in their courses.

Numerical Methods and Implementation in Geotechnical Engineering explains several numerical methods that are used in geotechnical engineering. The second part of this reference set includes more information on the distinct element method, geotechnical optimization analysis and reliability analysis. Information about relevant additional numerical methods is also provided in each chapter with problems where applicable. The authors have also presented different computer programs associated with the materials in this book set which will be useful to students learning how to apply the models explained in the text into practical situations when designing structures in locations with specific soil and rock settings.

This reference book set is a suitable textbook primer for civil engineering students as it provides a basic introduction to different numerical methods (classical and modern) in comprehensive readable volumes.

This book summarizes key information required for planning and implementing a healthy diet for patients based on sound nutritional concepts. Readers will find information on the background of nutrition in disease management and nutritional regulations in the USA. The book also describes macro- and micronutrients (including minerals and vitamins) and the applications of relevant nutritional concepts to real-life situations, using well-designed simulated clinical scenarios. Additionally, factors contributing to disease as well as the link between socio-economic status, culture and nutrition are discussed. This book should serve as useful handbook for nutritionists and health care providers and medical or pharmacology students taking courses in nutritional sciences.

Globalization and economic progress has been accompanied with an increase in the incidence of obesity, cardiovascular disease and other non-communicable illnesses worldwide among populations in some countries. Obesity and Disease examines how these rising epidemics of obesity and other lifestyle problems are changing health guidelines globally - from directing health care professionals on how to care for individuals to encouraging them to embrace the interconnected systems involved in chronic disease risk management, prevention and treatment. With a focus on systems, this reference serves as an excellent resource on how to develop a more comprehensive approach to population health. Starting with a systematic approach to health risk assessment in section one, followed by a targeted approach to risk reduction and prevention in section two, the eBook moves along seamlessly into section three calling for a shared responsibility toward strengthening health systems globally that can help determine and improve upon the health of individuals, and societies across the world.

Obesity and Disease gives applicable concepts to readers in a multidisciplinary and collaborative approach to alter health systems and implement changes that promote health and wellness in the communities they serve and live in. The information and resources in this eBook also serve as a guideline for collaborations across professional associations with a goal of developing strategic plans to combat obesity and diabetes.

In recent years, we have witnessed significant advances in obstetric anesthesia, providing greater safety for the mother and the fetus, as well as an improvement in pain management procedures during labor.

This volume presents updates in obstetrics and gynecology that are reflective of the changes in the demographics and associated clinical presentations of gynecological pathologies. It compiles state of the art information on the subject in 20 chapters contributed by more than 50 experts in obstetric anesthesia. The main objective of this volume is to inform and update readers about the different aspects essential to the practice of anesthesia and analgesia during pregnancy, labor, cesarean section and puerperium. The contents also include information about the management of pregnant women with different pathologies and high-risk pregnancies.

The authors believe that it is essential for all anesthesiologists to be aware of the latest advances and well-contrasted scientific evidence that will allow them to carry out their usual clinical activity.

The volume approaches the subject in a clear and didactic way for the benefit of all professionals involved in this field, including anesthesiologists, gynecologists, obstetricians, surgeons, clinicians and allied healthcare service providers.

This comprehensive handbook delves into the essence of Occupational Health and Safety (OHS), exploring the dynamic interplay between regulations, practical methodologies, and the broader impact of OHS on organizations. The goal of the book is to help readers understand OHS practices in the workplace and how to implement a plan. 

Chapter 1 establishes the conceptual framework of OHS and provides a foundational understanding of the subject. Moving forward, Chapters 2 and 3 dive into the international and national legal requirements, giving a comparative overview of OHS legislation in the EU and specific regulations in Romania, Italy, and Spain. 

Chapter 4 introduces readers to risk assessment tools and the OHS management process, while Chapter 5 emphasizes the importance of performance monitoring and measuring. 

Chapter 6 presents a step-by-step risk assessment methodology. 

Finally, Chapter 7 explores the significant impact of OHS on overall company performance, integrating ergonomics and organizational resilience. 

Key Features: 

Combines theoretical insights with practical applications for academics and OHS professionals. 

Offers an up-to-date analysis of OHS regulations, with a focus on EU guidelines and specific regulations for Romania, Italy, and Spain. 

Provides knowledge on risk assessment tools and performance monitoring methods for effective safety measures. 

Highlights the essential relationship between OHS and company performance with real-world examples and a systems approach. 

The book is ideal for a wide range of readers, including OHS trainees, professional safety managers, policymakers, researchers and students studying OHS practices, safety regulations and its organizational impact.

Oesophago-gastric Surgery is a reference manual which addresses the core knowledge needs of surgical trainees in oesophago-gastric surgery as well as established consultants in oesophago-gastric surgery and other specialties. The book features a practical and user-friendly format for the benefit of undergraduate and professional readers. The editors have carefully included information that aligns with gastroenterology specialization curricula.

Chapters in the first part cover all introductory topics about oesophagal and gastric surgery including anaesthesia, perioperative care, nutrition and physiology. This part concludes with details on various disorders of the oesophagus, Barret’s oesophagus, and reflux disease.

Older Women: Current and Future Challenges of Professionals With An Aging Population is about older women and the unique challenges they face now and in coming decades. Elderly women face problems that require response from multiple service providers in the social welfare, health care and legal sectors. Due to the complexity of the various issues and the multi-systemic responses required to address these problems among diverse groups, an interdisciplinary perspective in a multicultural context needs to be examined. This book is an attempt to explain the multidisciplinary facets of social work with elderly women. Readers are also introduced to the ethical issues and challenges caused by economic disparities and are also provided with guidelines on potential responses and intervention strategies to such difficulties. Readers are also introduced to the concept of cultural competence in terms of working with aged women.

The integration of theory, research and practice in this book makes it a valuable resource for academicians and working professionals who are or will be in frequent contact with older adults.

Multiple biotic and abiotic environmental factors may constitute stresses that affect plant growth and yield in crop species. Advances in plant physiology, genetics, and molecular biology have greatly improved our understanding of plant responses to stresses. This book details on technologies that have emerged during the past decade and have been useful in studying the multigenicity of the plant abiotic stress response. Upstream molecular mechanisms are involved in the plant response to abiotic stress, above all in the regulation of timings and amount of specific stress responses. Post-transcriptional mechanisms based on alternative splicing and RNA processing, as well as RNA silencing define the actual transcriptome supporting the stress response. Beyond protein phosphorylation, other post-translational modifications like ubiquitination and sumoylation regulate the activation of pre-existing molecules to ensure a prompt response to stress factors.

The text in this book deals with the importance of -omics approaches like Genomics, Metabolomics and Proteomics in abiotic stress tolerance. Large scale analytical approaches provide detailed information about the structure and complexity of signaling networks, identify subsets of genes or activities that are correlated to given stress factors and reveal unexpected or previously uncharacterized biochemical interactions.

To the best of our knowledge no book on -Omics studies in relation to Plant Abiotic Stress Tolerance is available in the market. This book should therefore be a valuable asset for the readers.

The Microfabrication technology has stimulated a plurality of lab-on-a-chip research for biomedical researchers and health care practitioners to manipulate and analyze complex biological fluids at the nano and microliter scale. Specifically, various miniaturized diagnostic devices have been developed for blood sample detection, which can increase diagnostic capacity significantly by enabling rapid, point-of-care chemical analysis. Recently, more and more researchers are paying attention to on-chip whole blood sample pretreatment, which is the focus of this eBook, aiming to form real Micro Total Analysis Systems (uTAS) for whole blood analysis by integrating blood sample pre-treatment and detection together.

The eBook consists of six chapters. Chapter 1 gives a brief introduction on the background of whole blood and the concept of µTAS, followed by a summary of specific microfluidic chips for whole blood pretreatment. Chapter 2 firstly reviews microfluidic chips for plasma isolation from whole blood samples with various methodologies (i.e., microfiltration, microcentrifugation, ultrasound, Zweifach–Fung effect and capillary effect). Then two examples using the plasma skimming effect and crossflow filtration respectively are discussed in detail. Chapter 3 firstly reviews microfluidic devices for blood cell filtrating, sorting and collection. Sorting methods such as size filtration, optical and magnetic manipulation, affinity separation, dielectrophoretic manipulation are covered and compared. Then a case study using crossflow filtration is analyzed in detail. Chapter 4 firstly reviews reported microfluidic devices for blood cell lysis in which mechanical lysis, sonication lysis, thermal lysis, electrical lysis, chemical lysis and optical lysis are covered. And then a cell lysis microchip using chemical agents for cell lysis is chosen as an example for further concept demonstration. Chapter 5 firstly reviews microfluidic devices for DNA extraction and purification by comparing reported methods of solid phase extraction, solid phase reversible immobilization and liquid/liquid extraction. And then two microchips with different solid phase matrixes are used for demonstration of chip based DNA extraction. Chapter 6 firstly reviews current integrated microfluidic platforms for blood pretreatment, followed by a case study.

Both fundamental analysis and specific applications are presented in this eBook, which is written for researchers, engineers, and advanced students who have research interest in whole blood pretreatment and miniaturized techniques.

We would like to express our appreciation to Bentham Science Publishers and their team members.

The internet provides a major source of exchanging health information through online portals and new media. Internet users can access health sites and online forums to obtain health information. In turn, these information sources act as a catalyst for wellbeing and improving personal health care behaviors and routines. Competent health institutions encourage the development of these individual behaviors that enable individuals to increase health empowerment and to take responsibility for their own health needs, diagnosis and treatment.

Online Health Forums and Services: Benefits, Risks and Perspectives is an investigation of the use of online health forums and services. The author first introduces the reader to the theories that define online social behaviors in terms of health care services. The chapters following this introduction attempt to account for the variations in online health care portal use and to what extent does social networking induce variations in health behaviors grounded in theory. A summary of media used for affecting health behavior change is also provided along with a discussion of the socioeconomic attributes of the individuals most likely to be affected in terms of their health behaviors.

The book provides a comprehensive perspective that links the aspects of the micro-level use of the Internet for health purposes (accessing health related websites, participation in health forums and networking sites) to the macro level practices of telemedicine. Readers will be able to understand the social and health characteristics of the different groups of patients and estimate the extent to which individuals in need of health and medical information are taking advantage of the availability of information and communication platforms to improve their health, or if they are being left behind. This is a timely reference for healthcare professionals, researchers and consultants involved in digital health care initiatives and public health administration who are seeking information about how access to online health information can influence lifestyles in a way that impacts human behavior in a positive, meaningful way.

The second volume of this book series presents a foundation for describing electron-field interactions, the basic elements involved in open quantum theory, the dissipative couplings of the active elements, the quantum injection dot electrons and coherent electromagnetic fields produced by crystal lattice vibrations. A microscopic description of the systems of interest is used to explain a number of structural models that describe electron arrangement and mechanics in such systems. The explanation of these models depends on a number of numerical parameters and calculations which have been explicitly discussed in detail. Readers will gain a better understanding of open quantum systems and energy conversion in semiconductor devices. Theoretical calculations presented in this book can also be compared with experimental data from prior experiments. The volume is also supplemented by an adequate bibliography which provides useful references.

This book is a handy text on advanced quantum theory for advanced physics and electronics students and researchers.

Open Quantum Physics and Environmental Heat Conversion into Usable Energy - Vol. 4 explores the intricate relationship between quantum mechanics, relativity, gravitation, and electromagnetism, offering insights into the dynamics of quantum particles in various fields. The book covers key phenomena such as spin, graviton spin, black holes, and quantum states in extreme conditions, including black hole formation. It explains how quantum particles behave as distributions of matter, using wave functions to describe their propagation. Further, it examines electromagnetic and gravitational field interactions, quantum particle transitions, Dirac's formalism of general relativity, and their applications in quantum electrodynamics and unified field theory.

Key Features:

- Detailed explanation of quantum particle dynamics and wave function theory.

- Discussion of quantum particle transitions and spinor fields.

- Exploration of black hole dynamics and gravitational wave interactions.

- Comprehensive coverage of unified field theory, integrating electromagnetism and gravity.

- Applications to quantum electrodynamics and particle collisions.

Opportunities for Biotechnology Research and Entrepreneurship explores the intersection of scientific innovation and entrepreneurial endeavors in the field of biotechnology. With a focus on addressing real-world challenges and creating transformative solutions, this book offers valuable insights into the diverse applications of biotechnology across ecology, food, industrial, and medical sciences. Comprising 20 chapters, this edited volume brings together contributions from experts around the globe, offering a comprehensive overview of emerging research trends and techniques. Each chapter provides necessary background information and presents current and future applications of biotechnology, making it an ideal resource for students, researchers, and industry professionals. Key features include global perspectives, concise summaries tailored for easy understanding, and updated data accompanied by illustrations and flow charts. Whether exploring environmental sustainability, enhancing food security, optimizing industrial processes, or advancing medical treatments, this book serves as a valuable reference for those interested in the dynamic field of biotechnology.

This handbook covers Optical Coherence Tomography Angiography (OCT-A) with a specific focus on choroidal and vitreoretinal disorders. It serves as an invaluable resource for teaching and aiding daily clinical decision-making in the field. Book chapters dissect the fundamentals of angiography through OCT, offering guidance on OCT-A and insights into macular perfusional findings across various vitreoretinal and choroidal pathologies. From diabetic retinopathy to autoimmune diseases and neovascularization, the book addresses prevalent vascular entities encountered in routine practice. Furthermore, it explores innovative approaches, including antivascular endothelial growth factor molecules and extended-release delivery devices, contributing significantly to the diagnostic and decision-making processes in clinical and surgical retina care. Each chapter is contributed by experts in the relevant subspecialty. Key Features: Practical, patient-centered guide emphasizing a clinical approach. Demonstrative clinical cases for enhanced understanding. Evaluation of perfusional indices using noninvasive and noncontact imaging techniques. High histopathological correlation of structural tissue characterization with microvascular evaluation. Exploration of new perfusion concepts and their role in disease pathogenesis. Part 2 covers advanced topics in OCT-A for choroidal and vitreoretinal disorders. Chapters explore macular perfusional repercussions in obstructive venous vascular phenomena, OCT-A findings in retinal infarction, and the role of macular perfusion in myopic macular traction maculopathy. Further discussions include postoperative perfusional findings in vitreoretinopathy, distinctions in choroidal vasculopathies, and the application of OCT-A in managing pathological choroidal neovascularization. The part concludes with a review of postoperative membrane formation, the usefulness of OCT-A in neurodegenerative diseases, and the evaluation of arterial occlusions and choroidal neovascularization management.

This book provides a comprehensive overview of current knowledge about research in oral infections and their association with cardiovascular diseases. Several epidemiological, clinical and other scientific aspects are covered in this book through the work of medical experts.

The detailed accounts in this book are of great value to readers in the scientific community, practitioners, teachers and students in relevant fields, and health-care planners.

Ordinary Differential Equations and Applications II: With Maple Illustrations integrates fundamental theories of Ordinary Differential Equations (ODEs) with practical applications and Maple-based solutions. This comprehensive textbook covers vector-valued differential equations, matrix solutions, stability methods, and periodic systems. Using Maple and MapleSim software, readers learn symbolic solutions, plotting techniques, 2D/3D animation for ODE problems, and simulations for engineering systems.

This book is ideal for undergraduate and postgraduate students in mathematics, physics, economics, and engineering, as well as researchers and professionals needing advanced applications of ODEs. Key Features:

- Comprehensive introduction to ODE concepts and real-life applications

- Solutions for initial value problems using Maple and MapleSim software

- Analysis of stability using Routh-Hurwitz and Lyapunov methods

- Models of neural firing, avian influenza, and biological populations

- Practical guidance on MapleSim for multi-domain simulations, code generation, and Monte Carlo simulation

Organic Spectroscopy: Technology and Applications is an essential guide to the principles and practices of spectroscopy in organic chemistry. This comprehensive text covers the fundamentals of the electromagnetic spectrum, UV-visible, infrared (IR), Raman, nuclear magnetic resonance (NMR), and mass spectrometry, providing a structured approach to understanding each technique`s role in molecular analysis. Designed for students and professionals alike, the book emphasizes problem-solving and structural analysis, offering a methodical progression through each technique to build practical expertise. Illustrated with detailed diagrams and real-world spectra, the text also includes solved examples to reinforce learning and enhance application skills.

Key Features:

- Comprehensive coverage of core spectroscopy techniques: UV-visible, IR, Raman, NMR, and mass spectrometry.

- Step-by-step explanations and problem-solving techniques for structural analysis.

- Numerous illustrations and spectra for visual learning.

Organoid Technology: Disease Modelling, Drug Discovery, and Personalized Medicine covers organoid technology emerging as a transformative platform in biomedical research. Chapters explain in detail the physiologically relevant in vitro 3D models that closely mimic human tissues and organs. This book provides a comprehensive overview of the development, application, and future potential of organoids in modern life sciences. It highlights the critical applications in disease modeling, regenerative medicine, and high-throughput drug screening.

Key Features:

Covers organ-specific organoid development and bioengineering methods

Discusses integration with emerging technologies such as nanotechnology

Includes insights into personalized medicine using patient-derived organoids

Covers details about the current regulatory and ethical landscapes in organoids-based research.

Thalassemia is one of the most common genetic diseases in the world. It has a relatively higher incidence in Mediterranean and Middle Eastern countries and presents a major public health and social challenge. This monograph updates the reader on the dental and orofacial characteristics of thalassemia major in Arab populations. Since very few detailed studies on these topics among Arabs have been published, the monograph attempts to bridge the knowledge gap in this area. Clinical, radiographic and odontometric features of the typical thalassemia major patient are clearly described in this book.

Key Features

- Provides a ready reference for dental and orofacial features in thalassemia major including a review of appropriate dental care

- Covers the pathogenesis, systemic complications, morbidity and mortality, management, and prevention of thalassemia major.

- Provides guidelines for optimal dental care.

- Covers special topics such as epidemiology, consanguinity, hematologic diagnosis, genetic testing, literature review, diet and nutrition, cost of treatment, and prevention

- Includes colored photographs, radiographs, drawings, tables, and 2 plates to illustrate examples and information

- Provides references for further reading

This monograph is a handy reference for medical and dental students, and caregivers on the subject of clinical dentistry in thalassemia patients.

"Orthodontic Treatment of Class III Malocclusion is a clinical textbook which highlights both research findings as well as clinical treatment of patients with Class III malocclusions. The volume equips readers with a critical review of present information about 1) the craniofacial biology behind various treatment strategies, 2) Diagnosis and treatment planning in both growing and non-growing Class III patients and 3) Contemporary orthodontic appliances using implants and miniscrews.

The book is divided into sections proving evidence-based research on the following aspects of Class III malocclusions: the genetic and epigenetic factors contemporary diagnosis and treatment planning for patients early treatment of Class III problems treatment of Class III problems in the adolescents surgical treatment of adult Class III patients treatment of Class III problems in patients with craniofacial anomalies

Orthodontic Treatment of Class III Malocclusion will empower clinicians with a sound knowledge about rationale for using certain treatment modalities and will help both general practitioners and specialists such as pediatric dentists and orthodontists to use this information for their daily practice."

This comprehensive compendium unravels the intricacies of three common and daunting skeletal disorders: osteoporosis, osteoarthritis, and rheumatoid arthritis. These ailments afflict people across all age groups, demanding a deeper understanding of their diagnostic, prognostic, preventive, and therapeutic dimensions. It presents seven key topics written by medical experts that explore research on these diseases: Chronic Lung Disease and Osteoporosis An exploration of the intricate link between chronic lung ailments and osteoporosis.

AI Detection of Knee Osteoarthritis Recent use of artificial intelligence aiding knee osteoarthritis identification. Inflammatory Signalling in Rheumatoid Arthritis Covers the role of cytokines and chemokines in the context of rheumatoid arthritis. Vitamin D, Immune System, and Bone Health Unveils the vital implications of Vitamin D on the immune system and bone health. Bone Water and Hydration Effects A review of the impact of drugs on bone hydration status through the lens of bone water. Dietary Patterns and Rheumatoid Arthritis An analysis of the connection between dietary habits and rheumatoid arthritis. Quality of Life in Rheumatoid Arthritis Patients (Chapters 112-130): An examination of the self-perceived quality of life in Rheumatoid Arthritis patients, comparing South Asian and British White populations. This knowledge-rich treatise is a valuable resource for patients and their families battling these skeletal ailments. It's equally beneficial for medical students, orthopedists, researchers, and anyone eager to grasp the complexities of these widespread skeletal pathologies.

With an increase of the population of elderly people in modern society due to advances in medicine and healthcare facilities, there is also an increase in the incidence and duration of chronic illnesses. Similarly, advanced age is considered a significant determinant of depression and poor quality of life. Additionally, the provision of therapies relevant to chronic diseases addresses the issues beyond the concept of cure, bringing to the center the need for a dignified quality of life of patients. An increased interest in quality of life is observed in patients who suffer from chronic diseases, including those with end-stage kidney disease (ESKD). End-stage kidney disease patients have a high burden of disease affecting their quality of life and dramatically shortening their life expectancy. Therefore, exploring quality of life issues among such patients becomes an essential task in the management of this population. This volume is written by researchers with a well-rounded understanding of the characteristics and impact of ESKD and provides a penetrating practical discussion to date of alternative approaches for comprehensively measuring the burden of end-stage kidney disease. Outcomes Assessment in End-Stage Kidney Disease focuses on the impact of this complex and exacting condition on patients and those that care for them. It also examines the economic impact of ESKD and the healthcare policy implications of this disease. It also brings comprehensive and thoughtful insights into the issues confronted by patients with ESKD to readers interested in nursing or medical caregiving, geriatrics and health psychology.

The considerable proliferation of new glasses during the second half of the 20th century (germanate,

vanadate, bismuthate, tellurite, chalchogenide glasses, etc.) brought about the use the plural form of the

4

generic glass denomination, in order to be able to index each emerging glass family by its proper name, as

well as to classify them methodically. Together with its great compositional versatility, the peculiar

characteristics of glass (non-crystalline structure with short-range order, continuous network with no

intergranular boundaries, isotropy, easy to be formed into a plastic state inside a wide temperature range)

allow for a freedom of design and adaptability that few materials are able to offer. All these circumstances

have contributed to the fact that, in the last seventy years, glass has acquired the multiple and varied

appearance of its new families, without losing neither its original image nor its soda-lime-silica traditional

composition, destined for the huge industrial manufacture of its conventional products.

Oxygen is historically entwined from its discovery with radical applications as a panacea by charlatans and by daring men constructing bridges using underwater caissons. Oxygen has made possible the exploration of the depths of the oceans beginning with hard-hat diving suits and extending to scuba gear, underwater habitats and submarines as well as space exploration. Molecular oxygen is critically involved in health and disease in more ways than any other element. It is essential for metabolism of food to nourish our bodies. Understanding its biological and chemical nature helps us to understand the effects of exercise, vitamins and supplements, and drugs used for cancer therapies.

Oxygen, the Breath of Life is a comprehensive reference on the historical, biological, chemical and medical aspects of oxygen. Readers, both laymen and experts, will gain knowledge of the basics of oxygen chemistry, how it functions in the human body, the role of oxidants in the development of various diseases. Chapters contain historical notes which highlight the discoveries of pioneering researchers.

Pain is a significant medical problem, as it is a factor in many diseases and debilitating conditions. The processing of pain in the body is a complex process which involves nerve signaling in the milieu of biochemical, molecular and genetic interactions occurring in the brain and other parts of the body. Pain, as a spokesperson of real and impending injury, outlives its usefulness as a warning signal and instead becomes chronic and excruciating. The transition of the realization of pain up to the cortical processing as a persistent condition represents an intricate process governed by the interaction of various factors. Research on humans and animals has led to the advent of personalized medicine where every patient can be treated according to the set of genes they possess. However, the genetic basis for pain has largely been undefined so far. Research on epigenetic alterations and micro-RNA (miRNA) in relation to the assessment and prevention of pain is still in infancy.

Pain: Causes, Concerns and Consequences focuses on pain in human diseases such as cardiac and non-cardiac disorders. This compendium on pain research offers basic information and useful updates on the pathology, genetics, and biomolecular pathways that cause pain. Additionally, readers will also learn about non-pharmacological therapies for pain. The monograph is a handy guide for medical students and doctors in different divisions such as oncology, surgery, neurology, psychiatry, psychology, physiotherapy and chiropractic care. The book also serves as a guide for life science researchers who are planning to develop methods to study pain in either a clinical or laboratory setting.

This book introduces the most recent research findings on selected parasitic weeds that occur in Jordan and are also spread in Middle Eastern countries. It is a valuable source of information for researchers, students as well as farmers, giving readers a better understanding of these regional parasites and their unusual growth patterns. The book set consists of two volumes. The first volume includes information about genera which are typically known as root parasites. These genera are Orobanchaceae, Santalaceae, and Cynomoriaceae families. The second volume covers stem parasites of the Cuscutaceae, Loranthaceae and Viscaceae families. The detailed information presented in this set makes this an essential reference on weeds and parasitic plants in Jordan and Middle Eastern regions.

Key Features:

- Chapters cover the biology, ecology, distribution, economic significance, host ranges, and control methods of a variety of regional weeds in an organized way

- It includes information on parasitic families, genera and species that are found in Jordanian flora and their hosts.

- It also provides coloured photos of weeds

- Presents the latest techniques for plant pest management

- Provides references for further reading

- Includes a glossary and appendix suitable for beginners

Passive Location Method Based on Phase Difference Measurement presents groundbreaking information for developing passive positioning technologies. The author has put forward a series of innovative solutions from the perspective of engineering application theory with the aim of giving a basic understanding of the application of unambiguous phase difference localization techniques for long-range passive detection.

On the basis of the existing linear solution of the double basis path difference positioning equation and the analysis of its intrinsic properties, this book starts from the study of the phase difference measurement method of the phase difference change rate, puts forward the concept of the differential function of the path difference per unit wavelength length and also discovers its jump law. It provides a possible way to solve the problem of unambiguous phase difference measurement. These results are of great significance to the development of passive localization techniques based on unambiguous phase difference measurement.

Key Features:

- Sequentially presents theoretical frameworks to build the readers knowledge for better understanding the topics

- Presents a variety of unique method for solving kinematic positioning parameters and Doppler signal parameters by using unambiguous phase difference measurement.

- Presents a variety of direction-finding and ranging methods based on short baseline array and using unambiguous phase difference measurement technology, and exhibits the method of constructing long baseline two-station direction finding and ranging with short baseline array

- Presents a variety of two-station passive positioning methods based on angle measurement which are beneficial to improve the positioning accuracy on the basis of studying the relationship between the phase difference and angle

- Presents the means to convert Doppler detection to the non-fuzzy phase difference measure, for the localization problem in which it is difficult to use the phase difference localization equation directly, since the accuracy of the phase difference measurement is better than that of the Doppler frequency difference

- Presents a variety of new positioning methods and several novel concepts while demonstrating the theoretical exploration of passive location problem based on unambiguous phase difference measurement

This reference is a resource for scholars, engineers and technicians involved in radio positioning research and the improvement of radar, satellite navigation systems, unmanned systems and Internet of Things infrastructure.

Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts is a comprehensive guide that explores the fundamental aspects, synthesis methods, and various applications of nanomaterials derived from plants. This book is designed for postgraduate researchers, engineers, and scientists in the fields of materials science, biotechnology, and chemical engineering, as well as other disciplines involved in nanomaterial production and applications.

The book delves into different plant-mediated nanomaterials, analyzing their synthesis mechanisms and discussing the regulation and application prospects of plant synthesis. It covers topics such as nanocellulose, biochar materials, plant exosomes, polyphenol nanoparticles, and the phytotoxicity and uptake of nanomaterials by plants. Additionally, it explores the research progress and applications of plant virus nanoparticles in the medical field, including drug delivery, molecular imaging, and vaccine preparation. Readers will be familiarized with the synthetic methods, characterization, and applications of green nanomaterials, paving the way for future studies on plants and their phytochemical constituents.

With its comprehensive coverage of plant-derived nanomaterials and their diverse applications, Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts serves as a valuable resource for researchers seeking to understand the potential of plants as sustainable sources for nanomaterial production.