Bentham Science Publishers

Machine learning is a subfield of artificial intelligence, broadly defined as a machine's capability to imitate intelligent human behavior. Like humans, machines become capable of making intelligent decisions by learning from their past experiences. Machine learning is being employed in many applications, including fraud detection and prevention, self-driving cars, recommendation systems, facial recognition technology, and intelligent computing. This book helps beginners learn the art and science of machine learning. It presens real-world examples that leverage the popular Python machine learning ecosystem,

The topics covered in this book include machine learning basics: supervised and unsupervised learning, linear regression and logistic regression, Support Vector Machines (SVMs). It also delves into special topics such as neural networks, theory of generalisation, and bias and fairness in machine learning. After reading this book, computer science and engineering students - at college and university levels - will receive a complete understanding of machine learning fundamentals and will be able to implement neural network solutions in information systems, and also extend them to their advantage.

The definition of occupational health hazards is constantly changing over time as technology advances and as the awareness of work place safety issues continues to grow. Introduction to Occupational Health Hazards focuses on work-related hazards which have evolved with the advent of more recent professions. The book introduces readers to the basic concept of occupational hazards. From this starting point, readers are introduced to the types of medical disorders that can occur as a result of occupational hazards, such as cancer and neurological disorders. The next section explains health hazards to medical and laboratory staff. The book concludes with a chapter that explains mental health issues (stress and psychosocial factors) that are related to occupational health – which is a recent addition to the spectrum of health risks in the working environment. As a handbook, the book provides information about occupational health risks for science and medical students along with professionals working in the health care and laboratory industries, respectively.

How do neurons work in processes that guide thought and action? This eBook answers this question by presenting an accurate analysis of all the physico-chemical phenomena occurring between interconnected neurons. Once researchers have this information, they can then build a functional catalog of neurons and understand the working behind the simplest physiological elements and these can hopefully be replicated into devices. Microscopic and macroscopic experimental results can assist in the study of sensorial analysis, instincts and motor control of skeletal muscles. The book also presents a description of memory at the cellular level and gives insights about the learning process in living systems. Such research has increased our understanding of the mechanisms of animal behaviors from the honeybee to the dog. In human beings, the efficiency of the same neural mechanisms overtakes a threshold when language allows building new abstract signals from previous abstract signals. Introduction to the Neural Basis of Action and Thought demonstrates to readers how physiological processes allow us to recall words and generate sentences and how these processes support abstract thought, action and self awareness. This book is a useful primer for anyone interested in cognitive sciences and related research.

This textbook is a primer for students on statistics. It covers basic statistical operations, an introduction to probability, distributions and regression. The book is divided into a series of 10 chapters covering a basic introduction to common topics for beginners. The goal of the book is to provide a sufficient understanding of how to organize and summarize datasets through descriptive and inferential statistics for good decision-making. A chapter on ethics also informs readers about best practices for using statistics in research and analysis. Topics covered: 1. Introduction to Statistics 2. Summarizing and Graphing 3. Basic Concepts of Probability 4. Discrete Random Variables 5. Continuous Random Variables 6. Sampling Distributions 7. Estimation 8. Hypothesis Testing 9. Correlation and Regression 10. Ethics

Ion Implantation and Activation presents the derivation process of related models in a comprehensive step by step manner starting from the fundamental processes and moving up into the more advanced theories.

Ion implantation can be expressed theoretically as a binary collision, and, experimentally using various mathematical functions. Readers can understand how to establish an ion implantation database by combining theory and experimental data. The models described in this ebook can be directly related to practical experimental data with various approaches: physical, empirical or experimental. Readers can also understand the approximations, and assumptions to reach these models. The redistribution and activation of implanted impurities during subsequent thermal processes are also important subjects and they are described in a broad manner with the combination of theory and experiment, even though many of the models are not well established. Chapters in the book explain, in depth, various topics such as Pearson functions, LSS theory, Monte Carlo simulations, Edgeworth Polynomials and much more.

This book provides advanced engineering and physics students and researchers with complete and coherent coverage of modern semiconductor process modeling. Readers can also benefit from this volume by acquiring the necessary information to improve contemporary process models by themselves.

Ion Implantation and Activation presents the derivation process of related models in a comprehensive step by step manner starting from the fundamental processes and moving up into the more advanced theories.

Ion implantation can be expressed theoretically as a binary collision, and, experimentally using various mathematical functions. Readers can understand how to establish an ion implantation database by combining theory and experimental data. The models described in this ebook can be directly related to practical experimental data with various approaches: physical, empirical or experimental. Readers can also understand the approximations, and assumptions to reach these models. The redistribution and activation of implanted impurities during subsequent thermal processes are also important subjects and they are described in a broad manner with the combination of theory and experiment, even though many of the models are not well established. Chapters in the book explain, in depth, various topics such as Pearson functions, LSS theory, Monte Carlo simulations, Edgeworth Polynomials and much more.

This book provides advanced engineering and physics students and researchers with complete and coherent coverage of modern semiconductor process modeling. Readers can also benefit from this volume by acquiring the necessary information to improve contemporary process models by themselves.

Ionic Liquids: Eco-friendly Substitutes for Surface and Interface Applications explores the growing interest in utilizing ionic liquids as sustainable alternatives for various industrial and biological applications. With their unique properties and environmentally friendly nature, ionic liquids have emerged as promising substitutes for toxic and volatile solvents, offering significant advantages in surface and interface chemistry.

This book is divided into two parts: Part 1 covers the basics of ionic liquids, their surface/interface properties, and interactions with metallic surfaces. Part 2 focuses on the wide range of surface and interface applications of ionic liquids, including wastewater treatment, corrosion protection, catalysis, separation processes, medical devices, and sensing applications.

Key Features:

A complete book fully dedicated to the surface and interface chemistry of ionic liquids with seventeen chapters

Covers fundamentals, recent progress, and applications in surface/interface chemistry

Presents up-to-date research and interdisciplinary insights

Includes relevant references and resources for further exploration

This is a valuable reference for scientists and engineers who want to learn about ionic liquids' chemistry and applications

The story of the unidentified serial killer in London's Whitechapel district - known as Jack The Ripper – has been the subject of interest to researchers for over 120 years. The name ascribed to the individual was from a letter sent to the Central News Agency in London on 27 September 1888. Initially thought to be a hoax, the letter gained much publicity when the writer's promise of clipping a lady's ears off manifested after the discovery of the body of Catherine Eddowes with an ear lobe severed, 3 days after the letter was received. Several letters followed this and borrowed elements from the earlier correspondences. Jack the Writer: A Verbal & Visual Analysis of the Ripper Correspondence is a different approach to the subject of 'Ripperology'. In this book, the author, Dirk Gibson, provides a quantitative content analysis of the letters. Gibson first grounds this study of the Jack the Ripper letters in an analysis of the legitimacy of the documents. The dialectic method is used to carefully consider the authenticity of these letters. The largest extant collection of Jack the Ripper letters is provided in this book, approximately 250 in number.

The most significant part of this book is a trio of content analyses quantifying the themes, subjects, people and linguistic mannerisms mentioned in the Ripper letters; the analyses describe precisely what was and was not in these missives. The letters are described and presented in the context of their content, with the valid letters presented in chronological order. Jack the Writer: A Verbal & Visual Analysis of the Ripper Correspondence will give readers, whether generally interested in the ripper correspondence or undertaking courses in criminology or abnormal psychology, a glimpse of the cultural context of a serial murderer's communication with the public and the press in Victorian times.

• Computing with Words and Granular Computing
• Extensions of fuzzy sets: intuitionistic fuzzy sets, hesitant fuzzy sets, neutrosophic sets, spherical fuzzy sets.
• Fuzzy Clustering
• Fuzzy Control
• Fuzzy Data Analysis, Fuzzy Clustering, Classification and Pattern Recognition
• Fuzzy Database
• Fuzzy Decision Making and Decision Support Systems
• Fuzzy Expert System
• Fuzzy Logic Systems
• Fuzzy Logic Techniques and Algorithms
• Fuzzy Mathematical Programming
• Fuzzy Mathematics
• Fuzzy Measure and integral
• Fuzzy Neural Systems, Neuro-Fuzzy Systems
• Fuzzy Pattern Recognition
• Fuzzy Process Control
• Fuzzy Reasoning System
• Fuzzy Sets in Bioinformatics
• Fuzzy System Applications in Computer Vision
• Fuzzy System Applications in E-commerce
• Fuzzy System Applications in Human-Machine Interface
• Fuzzy System Applications in Robotics, Sensors, Fuzzy Hardware and Architectures
• Fuzzy System in Multimedia and Web-Based Applications
• Fuzzy Systems Design and Optimization
• Fuzzy Systems Modeling and Identification
• Fuzzy Systems with Big Data and Cloud Computing, Fuzzy Analytics and Visualization
• Fuzzy-Rule Based System
• Hybrid Fuzzy Systems (fuzzy-neuro-evolutionary-rough)
• Possibility Theory and Imprecise Probabilit

• Preparation and characterization of new photocatalyst.
• Photocatalytic elimination of environmental pollutants in liquid or gas phase.
• Self-cleaning materials.
• Thin films.
• Photocatalytic syntheses of valuable products.
• Photocatalytic hydrogen generation and CO2 reduction.
• Kinetics and mechanistic aspects of photocatalytic reactions.
• Combination of photocatalysis with other technologies, such as membrane technologies and photoelectrocatalysis.
• Engineering aspects of photocatalytic processes.
• Homogeneous photocatalysis.
• Theory, modelling and computational aspects regarding the mechanisms of activation of photocatalysis.

Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science is an e-book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essence and diversity of genomics in contemporary science.

The third volume of this ebook series features a variety of articles exploring oncogenomics, mouse genetics, feline genetics, genetic mechanism for pain, the genetics of weeds and much more.

This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design.

Part II of the book set covers these topics:

- Anticancer targets for heterocyclic lead compounds

- Coumarin hybrids for cancer treatments - Progress in nitrogen and sulphur-based heterocyclic compounds for their anticancer activity

- Imidazole as an anticancer heterocyclic ring - Morpholine for profiling anticancer lead compounds

- Natural products as anticancer agents

Kidney transplantation is worldwide considered the best replacement therapy in patients with end-stage renal disease. However, although impressive improvements in surgical techniques and in the management of immunosuppression, long-term results have not significantly changed over the last decades.

The purpose of this book is not to be a comprehensive review on kidney transplantation, but it would overview the recent acquisitions in the field of kidney transplantation, by offering to clinicians the future directions and the possible fields of research to improve the long term outcome.

The book is divided into 27 chapters. The first part of the book is devoted to the basic principles of immunity and organ transplantation and the clinical evaluation of potential recipient. Moreover, in this section are discussed the most recent strategies to increase the donor pool trying to offer a kidney transplantation to a growing number of patients. The second part of the book is devoted to the immunosuppression. In these two chapters, the authors present an overview on the immunosuppressive management of kidney transplant recipients, with particular emphasis on the minimization of immunosuppression. The third part of the book is devoted to the complications of immunosuppression and to the psychological aspects of transplantation. This section is particularly detailed, and offers a complete point of view on the consequences and benefits of kidney transplantation. Last section is devoted to the future. The clinical tolerance and xenotransplantation are not still the present, but the authors illustrate the fields of application of these fundamental aspects of organ transplantation.

The authors and editors have tried to select an appropriate mix of citations, but it has not been possible to cite all the relevant articles. Apologies are due to those authors whose works we have failed to cite.

Our goal was to provide the most recent acquisitions in a practical manner. We hope that we have succeeded.

Special thanks to all the authors for their excellent and enthusiastic collaboration and special thanks to our patients to whom are dedicated all our efforts.

The phenomenon of resistance to motion through a fluid is believed to be a function of fluid-wall interaction. This theory is based on the assumption that under certain conditions a real fluid does not usually slip on the wall in contact with it and displays laminar flow. This set of conditions is known as a ‘no slip boundary condition’. But if a fluid is passed alongside a wall, the drag reduction in the laminar flow region can be calculated. In Laminar Drag Reduction, the frictional drag of an internal or an external fluid flow along a certain kind of hydrophobic wall is investigated. An analytic approach towards the mechanism of drag reduction is employed using Navier-Stokes existence and smoothness equations. The experimental results presented in this book show that frictional drag of a fluid alongside this hydrophobic wall decreases in comparison with fluid flow along a conventional wall or surface.

This form of laminar drag reduction represents a relatively new area of research, where the laminar flow can be controlled by microscopic surface modifications, allowing fluid flows to slip over a wall. Laminar Drag Reduction brings information about some interesting phenomena related to fluid slippage on a highly water-repellent surface. Readers, physics graduates and senior researchers alike, can benefit from the information presented in this book to tackle more challenging questions in fluid mechanics research.

This monograph is a collection of reviews that presents results obtained from new and somewhat unconventional methods used to fight multiple drug resistance (MDR) acquired by microorganisms and tumours. Two directions are considered: (i) the modification of non-antibiotic medicines by exposure to un-coherent, or laser optical radiation to obtain photoproducts that receive bactericidal or, possibly, tumouricidal properties and (ii) the development of new vectors (micrometric droplets of solutions containing medicinal agents) to transport medicines to targets based on optical and micro spectroscopic methods.

Chapters shed light on pendant droplets used for antibiotic drug delivery, the science of lasers and their interactions with fluids in pendant droplets and spectroscopic analyses of droplets used to treat MDR infections. It therefore equips researchers and medical professionals with information about tools that enable them to respond to medical emergencies in challenging environments.

The intended readership for this monograph includes graduate students, medical doctors, fluid physicists, biologists, photochemists, and experts in drug delivery methods employed in extreme conditions (such as those found in outer space and hypergravity conditions) who are learning about using techniques such as laser spectroscopy, biophotonics and optofluidics/microfluidics.

This E-book covers the main aspects about the benefits of omega-3 long chain polyunsaturated fatty acids (LC-PUFAs) to human health. The knowledge of physiological effects of LC-PUFAs at different levels is constantly expanding. Topics covered over 10 chapters thoroughly detail the role of omega-3 LCPUFAs in nutrition (gene regulation) and disease (clinical applications); information about food sources and recent intake recommendations is also explained. This book also discusses current data concerning the role of LC-PUFAs during pregnancy and lactation, in cognitive function, immune response, allergy, asthma, cardiovascular diseases, depression, obesity, and insulin resistance. The book should be useful for advanced graduate students, public health officials as well as researchers working with LC-PUFAs.

Publications on non profit management reflect three main trends. Some books describe the nonprofit experience in different countries focusing on how these experiences reflect the case of a particular organization in its specific cultural context. These case studies provide an interesting, but not representative, documentation of the issues to be discussed. On the opposite end, other books introduce theoretical approaches and conceptual models that investigate the emergence of the nonprofit phenomenon in a comparative way. Finally, some other books focus on developing the understanding and provide the guidelines on specific themes e.g. accountability, change, marketing etc. Learning Why and How, in contrast to the above, accounts for a comprehensive view of the organizational complexity of management in the nonprofit sector.

This e-book provides a systemic view of nonprofit organizations linking micro and macro level aspects of management. It combines sociological, organizational and psychological elements of organization studies and provides an in-depth understanding of various issues and dilemmas among readers, students and executives of nonprofit organizations and civil society.

Lifestyle diseases and related conditions present a major healthcare challenge for children, posing a significant threat to their well-being. The Editors have compiled chapters to present a multicentric approach to the subject.

This book is an insightful reference on lifestyle diseases and its management in adolescents. It includes ten chapters with a focus on systemic disorders that are linked to lifestyle issues. Topics in this volume include gut microbiome and gastrointestinal disorders, neurological disorders, dental diseases, respiratory diseases and allergies associated with pesticides, cancer, hypertension, cardiovascular disorders, diabetes, polycystic ovarian syndrome, and common infectious diseases.

The book highlights the risk factors and determinants of these diseases, and where an immediate intervention is needed. An updated understanding of the diseases with scientific references gives readers crucial information for setting the groundwork for long-term public health policy formulation.

This book serves as a primary resource for scholars and trainees in nursing, medical (pediatrics and endocrinology) and paramedical courses who are required to understand lifestyle diseases with a focus on adolescents. Readers and professionals in public health, life-sciences and related disciplines can also use this as a secondary reference.

This brief monograph provides reports on liquid crystal materials used for specific devices designed for industrial applications. The authors of each chapter present insights on the design and technical aspects of the manufacturing of advanced liquid crystal light modulators reflecting their experience in advanced liquid crystal materials science.

Chapters in the book first introduce readers to the chemistry and basic materials science of liquid crystal light modulators with information important for practical situations such as custom manufacturing and material quality assessment (including the determination of Frank elastic constants). Subsequent chapters cover a selection of interesting projects where liquid crystal light modulators are applied, such as: a highly transparent, laser damage resistant liquid crystal phase modulators for space-borne laser rangefinders; a dynamic optical filter designed for visualization of air pollution; a high contrast, fast operating, outdoor light shutter for the eye protection of welders.

Readers will gain an awareness of the peculiarities of the liquid crystalline matter, along with the complexity of the design and fabrication of active optical elements, as the information provided in this volume presents detailed practical results of the liquid crystal technology projects.

This textbook presents basic principles of local anesthesia and exodontia for undergraduate dental program students and dental surgeons in training. Readers will understand key concepts and points that prepare them for daily oral and maxillofacial surgery practice. The book also provides detailed notes for managing patients who have different medical conditions such as cardiovascular diseases, endocrine disorders and systemic diseases.

Key Features:

- provides an easy to understand short note format of information for readers

- covers the basics of anesthesia and pain biology

- covers simple extractions to complex surgical extractions

- presents guidelines for managing patients with medical complications

Contemporary Endoscopic Spine Surgery brings the reader the most

up-to-date information on the endoscopy of the spine. Key opinion

leaders from around the world have come together to present the

clinical evidence behind their competitive endoscopic spinal surgery

protocols. Chapters in the series cover a range of aspects of spine

surgery including spinal pain generators, preoperative workup with

modern independent predictors of favorable clinical outcomes with

endoscopy, anesthesia in an outpatient setting, management of

complications, and a fresh look at technology advances in a historical

context. The reader will have a first-row seat during the illustrative

discussions of expanded surgical indications from herniated disc to

more complex clinical problems, including stenosis, instability, and

deformity in patients with advanced degenerative disease of the human

spine. Contemporary Endoscopic Spine Surgery is divided into three

volumes: Cervical Spine, Lumbar Spine, and Advanced Technologies to

capture an accurate snapshot in time of this fast-moving field. It is

intended as a comprehensive go-to reference text for surgeons in

graduate residency and postgraduate fellowship training programs and

for practicing spine surgeons interested in looking for the scientific

foundation for their practice expansion into endoscopic surgery.

This volume (Lumbar Spine) covers the following topics in 18 detailed chapters:

Lumbar endoscopy: historical perspectives, present, and future

Endoscopic lumbar discectomy - anatomy, nomenclature, indications and

advanced techniques

Current approaches for the treatment of endstage vacuum degenerative

lumbar disc disease

Advanced endoscopic techniques of lumbar foraminotomy and treatment of

degenerative spondylolisthesis

Endoscopic treatment of lumbar facet cysts

Endoscopic techniques for the treatment of a wide range of chronic low back pain

Endoscopic spine surgery techniques in the elderly

Endoscopic fusion techniques

Endoscopic resection of schwannoma

Technical notes for difficult cases, controversies and complications

of lumbar endoscopy.

This reference presents basic concepts relevant to respiratory function in normal and diseased states.The volume stresses a quantitative approach to physical parameters used as indicators of normal and diseased physiological respiratory function. The contents of this reference allow medical students and physiology researchers to become "clinical detectives" - by presenting information that can be useful for enhancing their understanding of the major abnormalities in terms of ventilation, pulmonary blood perfusion, venous admixture, wasted alveolar ventilation, tissue oxygenation, acid-base balance, respiratory mechanics, control of breathing, etc.

This book is intended for first and second year medical students as well as for residents and fellows, especially in disciplines such as anesthesiology and pulmonary medicine. In addition, the unique mechanistic approach of this book also provides a useful reference for teachers of respiratory physiology who are not involved in respiratory research or those who have not been specifically trained in organ-system physiology. This book thus fills this gap by providing a modern physiology faculty some tools for learning the "nuts-and-bolts" of lung physiology and associated respiratory care.

Today's academic environment presents assessment challenges defined by an increased volume of available information coupled with increased competition among students and time constraints. Multiple choice questions (MCQs) provide examiners with an opportunity to assess academic performance on the basis of instant recollection of correct answers in a minimal amount of time.

MCQs Series for Life Sciences Volume 1 is a collection of MCQs on advanced topics and offers the following benefits for readers:

Includes over 2600 relevant MCQs

Covers five advanced subjects including biochemistry, cell biology, developmental biology, genetics & molecular biology and immunology.

Simplified language and presentation of concepts

Answers to each question are provided

This MCQs eBook series in life sciences is, therefore, a handy reference for graduate and postgraduate students undertaking examinations or entrance tests as well as teachers or examiners involved in setting and controlling assessments in specific subjects in life sciences.

This book presents use-cases of IoT, AI and Machine Learning (ML) for healthcare delivery and medical devices. It compiles 15 topics that discuss the applications, opportunities, and future trends of machine intelligence in the medical domain. The objective of the book is to demonstrate how these technologies can be used to keep patients safe and healthy and, at the same time, to empower physicians to deliver superior care. Readers will be familiarized with core principles, algorithms, protocols, emerging trends, security problems, and the latest concepts in e-healthcare services. It also includes a quick overview of deep feed forward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, practical methodology, and how they can be used to provide better solutions to healthcare related issues. The book is a timely update for basic and advanced readers in medicine, biomedical engineering, and computer science. Key topics covered in the book: o An introduction to the concept of the Internet of Medical Things (IoMT). o Cloud-edge based IoMT architecture and performance optimization in the context of Medical Big Data. o A comprehensive survey on different IoMT interference mitigation techniques for Wireless Body Area Networks (WBANs). o Artificial Intelligence and the Internet of Medical Things. o A review of new machine learning and AI solutions in different medical areas. o A Deep Learning based solution to optimize obstacle recognition for visually impaired patients. o A survey of the latest breakthroughs in Brain-Computer Interfaces and their applications. o Deep Learning for brain tumor detection. o Blockchain and patient data management.

Machine Learning and Its Application: A Quick Guide for Beginners aims to cover most of the core topics required for study in machine learning curricula included in university and college courses. The textbook introduces readers to central concepts in machine learning and artificial intelligence, which include the types of machine learning algorithms and the statistical knowledge required for devising relevant computer algorithms. The book also covers advanced topics such as deep learning and feature engineering.

Key features:

- 8 organized chapters on core concepts of machine learning for learners

- Accessible text for beginners unfamiliar with complex mathematical concepts

- Introductory topics are included, including supervised learning, unsupervised learning, reinforcement learning and predictive statistics

- Advanced topics such as deep learning and feature engineering provide additional information

- Introduces readers to python programming with examples of code for understanding and practice

- Includes a summary of the text and a dedicated section for references

Machine Learning and Its Application: A Quick Guide for Beginners is an essential book for students and learners who want to understand the basics of machine learning and equip themselves with the knowledge to write algorithms for intelligent data processing applications.

Male Infertility: An Integrative Manual of Western and Chinese Medicine is a holistic manual on male infertility for the medical practitioner. The book integrates the conventional (or Western) medical approach to male infertility with traditional Chinese medicine.

Key Features:

- information about several aspects of male reproductive medicine (anatomy, physiology diagnosis, fertility treatments)

- information about the role of traditional Chinese medicine in treatment of male infertility (including energetic anatomy and Qi concepts)

- complete guide to acupuncture techniques

- easy-to-consult tables and appendices for quick reference

The unique, integrated approach to addressing male infertility makes this handbook essential reading for practicing and training andrologists, Chinese medicine practitioners, acupuncturists, as well as researchers and counsellors in the field of reproductive medicine.

Frontiers in Arthritis is an eBook series devoted to publishing the latest and the most important advances in arthritis research. Each volume brings together contributions from rheumatologists ad orthopedic specialists on the diagnosis, management and treatment of arthritis. The series also puts a focus on strategies for managing pain in patients in both pre and post operative situations.

Management of Osteoarthritis - A holistic view provides information about osteoarthritis of the knee and hip. Chapters explain osteoarthritis pathology and therapy (nutritional, exercise and surgical). The volume also covers different therapies such as viscosupplementation, platelet rich plasma injections, biologicals (amniotic membranes) and surgical options aimed at alleviating pain. The book is an ideal quick reference guide for medical students and nursing staff.

Explore the world of advanced materials and their manufacturing processes through this authoritative and enlightening reference. Discover how these innovations are shaping the future of high-tech industries and making a profound impact on our world. Manufacturing and Processing of Advanced Materials compiles current research and updates on development efforts in advanced materials, manufacturing, and their engineering applications. The book presents 22 peer-reviewed chapters that cover new materials and manufacturing processes. Key Topics Materials for the Future: Properties, classifications, and harmful effects of advanced engineering Innovative Manufacturing Techniques: Nanotechnology in material processing and manufacturing innovation. Advanced Welding and Joining: laser welding and friction stir welding in manufacturing composite materials. Sustainable Practices: 4. Eco-Friendly machining, water vapor cutting fluid, for high-speed milling., natural fiber reinforcement with materials like bamboo leaves. Advanced Materials Characterization and Modeling: Carbon nanotube (CNT)-reinforced nanocomposites and tribology for durable and reliable materials ensuring reliability. Materials for Energy and Electronics: Energy Storage Innovations and smart materials for electronic devices Novel Drilling and Machining Processes: Microwave drilling, electric discharge machining and die-sinking electric discharge machining for metal matrix composites. Innovations in Nanoparticle Production: Spark discharge method (SDM) for advanced nanoparticle production. The book caters to a diverse audience, offering an invaluable resource for researchers, engineers, graduate students, and professionals in materials science, engineering, chemistry, and physics. By enhancing their knowledge and expertise, readers are poised to become key contributors to various industries and technological advancements.

This reference highlights the significance of marine ecosystems, encompassing seaweed beds, seagrasses, coral reefs, mangroves, estuaries, and protected areas, as a remarkable gateway to overcoming healthcare challenges and unlocking a rich trove of bioactive compounds for drug discovery.

One of the key highlights of this book is its exploration of the development of marine bio-drugs, a field that demands collaboration among scientists from both academic and industrial fronts. The editors also include a prospective review on marine environments, emphasizing the necessity for big data, collective knowledge sharing, financial support, and streamlined administrative processes, all of which contribute to enhancing innovation in the drug discovery process. Another feature includes reference lists that allow researchers to explore topics of interest in depth.

With twelve comprehensive chapters, this book extensively covers marine ecosystem biodiversity, productivity, protected areas, and the intricate interplay of biotic and abiotic factors that shape these ecosystems. Readers will learn about important bioactive compounds within marine organisms and how to use this knowledge to outline a strategy for bio-drug discovery. The book caters to a diverse audience of researchers, students, ecologists, microbiologists, pharmacologists, and biotechnologists who are engaged in studying the dynamic components of marine environments. By providing the latest insights and strategies in the realm of bio-drug discovery from marine resources, this book serves as an invaluable resource for scholars and professionals seeking to tap into the potential of these unique ecosystems.

Many studies on environmental and business sustainability have been conducted over the last couple of decades. These studies demonstrate that the concept of sustainability management can be applied to several industries. Consumers around the globe are increasingly interested in sustainable consumption and they turn their attention into sustainable products, thus, campaigning for banning companies and supply chains that do not operate under sustainable ethos.

Markets, Business and Sustainability is a collection of selected reports that examine business sustainability, market sustainability and supply chain sustainability in a variety of contexts and using diverse methodologies. This reference work emphasizes the profound impact of sustainability management on markets and business. Readers are presented with critical analyses on different dimensions of sustainability. This book covers the applications of sustainable management techniques in construction, city logistics and the food industry.

Sustainability management practitioners, consumers, as well as students and academics can enrich their understanding about the business dimension of sustainability and also find references of available literature on the subject. The information presented in this reference is also helpful to senior business leaders seeking to create a vision, mission and strategy for their companies in order to create sustainable value, and an organizational culture of sustainability.

Marvels of Artificial and Computational Intelligence in Life Sciences is a primer for scholars and students who are interested in the applications of artificial intelligence (AI) and computational intelligence (CI) in life sciences and other industries.

The book consists of 16 chapters (9 of which focus on AI and 7 of which showcase the benefits of CI approaches to solve specific problems). Chapters are edited by subject experts who describe the roles and applications of AI and CI in different parts of our lives in a concise and lucid manner. The book covers the following key themes:

AI Revolution in Healthcare and Drug Discovery: AI's Impact on Biology and Energy Management AI and CI in Physical Sciences and Predictive Modeling Computational Biology The editors have compiled a good blend of topics in applied science and engineering to give readers a clear understanding of the multidisciplinary nature of the two facets of computing. Each chapter includes references for advanced readers.

The world faces significant challenges as the population and consumption continue to grow while fossil fuels and other raw materials are depleted at ever-increasing rates. Environmental consciousness and a penchant for thinking about material cycles have caught on with consumers. Therefore, the use of environmentally compatible materials and sustainable production methods are now desired. Materials and Technologies for a Green Environment discusses the major issues surrounding the production of energy through biofuels and waste management. It comprises seven chapters that cover various fields of interest to readers involved in environmental management and sustainability planning. The topics covered include renewable energy sources, thermoelectric generators, electric vehicles, biodiesel production from poultry waste, scramjet combustion engines, and sustainable architecture for green buildings. Given its scope, this book is a valuable resource for students, researchers and engineers in environmental science, mechanical engineering, and chemical engineering and sustainability studies.

This book focuses on cases and studies of interest to mechanical engineers and industrial technicians. The considered applications in this volume are widely used in several industrial fields particularly in the automotive and aviation industries. Readers will understand the theory and techniques which are used in each application covered in each chapter.

The book contents include the following topics:

Numerical analysis of hydrokinetic turbines

Computational fluid dynamics of a CuO based nanofluid in mini-channel cross-sections

Orthodontic biomechanics of a NiTi arch wires

Reynold's number effects on fluid flow through Savonius rotors

Effect of operating parameters on Zn-Mn alloys deposited from additive-free chloride bath

Optical properties and stability of a blue-emitting phosphor (Sr2P2O7:Eu2+) Under UV and VUV excitation

Numerical study of the influence of nanofluid type on thermal improvement in a three dimensional mini channel

Electrochemical studies and characterization of Zn-Mn coatings deposited in the presence of novel organic additives

Prediction of fire and smoke propagation under a range of external conditions

Structural design of a 10 kW H-Darrieus wind turbine

The presented case studies and development approaches aim to provide the readers, such as graduate students, PhD candidates and professionals with basic and applied information broadly related to mechanical engineering and technology.

This book focuses on cases and studies of interest to mechanical engineers and industrial technicians. The considered applications in this volume are widely used in several industrial fields particularly in the automotive and aviation industries. Readers will understand the theory and techniques which are used in each application covered in each chapter.

Volume 3 includes the following topics:

Numerical simulations of three-dimensional laminar mixed convection heat transfer of water-based-Al2O3 nanofluid in an open cubic cavity with a heated block.

Nonlinear formulations of Element-Free Galerkin Method (EFGM) for large deformation analysis of Ogden's hyperelastic materials, emphasizing incompressibility and mesh distortion avoidance.

Development of a 3D numerical model with LS-DYNA using a coupled SPH-FEM method to simulate hydraulic behavior of a Ski-Jump Spillway with dentates, showcasing precision through validation.

Exploration of enhancing the inlet system of an LPG-H2 fueled engine using a static inclined blade turbine, analyzed through Computational Fluid Dynamics (CFD) simulations.

Effective utilization of Artificial Neural Networks (ANN) in heat transfer applications, addressing issues like fouling in heat exchangers, showcasing their accuracy compared to experimental data.

Investigation of the impact of nitrogen concentration on the structure and properties of ZrN coatings deposited by magnetron sputtering, evaluating variations in structural and mechanical properties.

Forced convection in a horizontal cylindrical pipe with pseudoplastic fluid, considering uniform constant heat flux and uniform temperature as boundary conditions.

Modeling and experimental study of a water solar collector coupled to an optimized solar still, aiming to enhance freshwater production in a solar distillation system under specific climatic conditions.

Exploration of the effect of film thickness on the structure and properties of Ti-N films deposited by magnetron sputtering, utilizing theoretical and experimental analysis to confirm the rock salt TiN structure.

The presented case studies and development approaches aim to provide readers with basic and applied information broadly related to mechanical engineering and technology.

Present day mechatronic systems are designed with synergistic integration of mechanics, electronics and computer technology to produce intelligent devices for the purpose of solving real-world problems. Crucial requirements for a mechatronic system are robustness and fault tolerance, i.e. it should have the ability to process incomplete, imprecise or uncertain information. Such systems often have to work in collaborative environments while being subjected to adverse conditions yet adhering to strict safety standards. This e-book explains the fundamentals of designing such systems from the first principles and how to embed intelligence into them. Examples in this volume are not restricted to production lines, but extend to extreme safety based systems such as space and underwater robotics, autonomous transportation systems, aviation systems and medical robots. Moreover, this e-book also presents recent developments in the design of innovative and intelligent mechatronic systems, applied to robotics and transportation systems, thereby providing an authoritative support for researchers and professionals having basic knowledge in mechatronics.

Beta-glucan is a polysaccharide and an important food supplement that strengthens the immune system. Beta-glucan can be obtained from many food sources such as mushrooms, yeast, or oats. Beta-glucan has a therapeutic use in the treatment of many diseases, thanks to its immune system strengthening effect. Its use helps curtail the need for administering high levels of antibiotics in case of serious infections.

This book presents information about the medical applications of beta-glucan. Starting with an introduction to the basic biochemistry and classification of beta-glucan, the contents explain the readers about its use in treating a variety of medical conditions. These include cancer, allergies, COVID-19, respiratory tract infections, hypercholesterolemia, diabetes and many other other endocrinological, immunological and infectious diseases.

This book is a comprehensive resource about the medical use of beta-glucan where any reader can find topical information and learn about recent studies on the therapeutic effects of beta-glucan on the treatment of different diseases.

Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook intended for students taking courses in the various fields of medicinal chemistry, pharmacy, medical and dental programs. Moreover, people working in the pharmaceutical industry and doctors preparing for Medical Board Exams will also find it useful. Since, new drugs are being developed by multi-disciplinary teams; this E-Book describes new paradigms that are emerging in modern biology, biochemistry and medicine. It is therefore a fusion of traditional and western medicine and between systems thinking and reductionist thinking. Readers will learn about how new drugs are investigated, developed and eventually approved by the FDA. The book also includes important information about cGMP, GLP and the FDA regulatory requirements, the importance of environmental toxins, such as bisphenol A (BPA) and perfluorooctanoic acid (PFOAA) in autoimmune diseases and health. This book offers exceptional value in its descriptions of RNA, epigenetics, toxicology, new drug development, genetically modified organisms and analytical chemistry that cannot be found in other textbooks.

Medicinal Chemistry - Fusion of Traditional and Western Medicine is a textbook intended for students taking courses in the various fields of medicinal chemistry, pharmacy, medical and dental programs. Moreover, people working in the pharmaceutical industry and doctors preparing for Medical Board Exams will also find it useful. Since, new drugs are being developed by multi-disciplinary teams; this E-Book describes new paradigms that are emerging in modern biology, biochemistry and medicine. It is therefore a fusion of traditional and western medicine and between systems thinking and reductionist thinking.

The 3rd edition attempts to explain the predictive, preventive, personalized and participatory (P4) paradigm of medicinal chemistry. This edition features new chapters focusing on personalized medicinal chemistry and the endocrine system (with a discussion of bioidentical hormone therapy). Other chapters cover the disease mechanism and associated pharmacology of drugs for several diseases including cancer, metabolic syndrome, diabetes, heart disease, stroke, osteoporosis, neurodegenerative diseases, the immune system and much more. The new edition also includes an overview of emergent medical problems and possible solutions (such as the flu, ebola virus, global climate change, a shortage of medicines, genetic engineering and stem cell therapy). Drugs that have been approved by the FDA since the 1st edition was written are also included. The book concludes with an explanation of systems thinking in medicinal chemistry, an important, yet rarely explored topic in other medicinal chemistry text books.

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of chemical basis of drug action. This first volume of the series is comprised of 8 chapters focusing on basic background information about medicinal chemistry. It takes a succinct and conceptual approach to introducing important fundamental concepts required for a clear understanding of various facets of pharmacotherapeutic agents, drug metabolism and important biosynthetic pathways that are relevant to drug action. Notable topics covered in this first volume include the scope and importance of medicinal chemistry in pharmacy education, a comprehensive discussion of the organic functional groups present in drugs, and information about four major types of biomolecules (proteins, carbohydrates, lipids, nucleic acids) and key heterocyclic ring systems. The concepts of acid-base chemistry and salt formation, and their applications to the drug action and design follow thereafter. These include concepts of solubility and lipid-water partition coefficient (LWPC), isosterism, stereochemical properties, mechanisms of drug action, drug receptor interactions critical for pharmacological responses of drugs, and much more. Students and teachers will be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body.

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of the chemical basis of drug action. Medicinal Chemistry of Drugs Affecting the Nervous System is the second volume of the series and it presents 8 chapters focusing on a comprehensive account of drugs affecting the nervous system. The volume informs readers about the medicinal chemistry of relevant drugs, which includes the mechanism of drug action, detail structure activity relationships and metabolism as well as clinical significance of drugs affecting autonomic and central nervous system. Chapters in this volume cover cholinergic drugs, adrenergic drugs, antipsychotics, antidepressants, sedatives, hypnotics, anxiolytics, antiepileptic drugs, anesthetics and antiparkinsonian drugs, respectively. Students and teachers will be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body. The information offered by the book chapters will give readers a strong neuropharmacology knowledge base required for a practicing pharmacist.

This comprehensive reference explores medicinal plants, phytomedicines, and traditional herbal remedies as potential sources for the prevention and treatment of COVID-19. It features 9 chapters authored and edited by renowned experts. The book specifically highlights the promising drug discovery opportunities grounded in bioactive compounds from medicinal plants and herbal medicines, offering insights into combatting SARS-CoV-2 infections and respiratory complications.

Key Highlights:

Drug Discovery Potential: Explores the vast potential of medicinal plants, phytomedicine, and traditional remedies against COVID-19, shedding light on groundbreaking drug discovery avenues.

Cutting-Edge Insights: Provides up-to-date insights into the use of medicinal plants, herbal drugs, and traditional medicines in the fight against COVID-19.

Natural Immune Boosters: Details the use of indigenous herbs, spices, functional foods, and herbal drugs for boosting immunity and preventing SARS-CoV-2 infections.

Drug Repurposing: Highlights innovative drug repurposing strategies using phytomedicine-derived bioactive compounds and phytochemical databases for COVID-19 drug development. Additional features of the book include a reader-friendly introduction to each topic and a list of references for advanced readers. This timely reference is an informative resource for a broad range of readers interested in strategies to control COVID-19, including postgraduate researchers, and pharmaceutical R&D experts. It also serves as a handbook for professionals in clinical and herbal medicine.

This book provides readers a fundamental understanding of the science and applications of medicinal and aromatic plant materials. Chapters of this handbook covers the basics of ethnobotany, (bio)active compounds and their natural sources. Information about the cosmetic, nutritional, medicinal and industrial uses (dyes, tannins and biocides) is also presented. Readers will also learn about concepts central to quality control processes, sustainable management, wild harvesting and the economic valuation of the industrial impact of endemic plants.

The volume also presents a case study of the wormwood (Artemisia absinthium L.), which is helpful in explaining the above concepts.

This book is intended as a handbook for undergraduate students and teaching professionals in research and higher education institutions involved in agricultural engineering, pharmacy, forestry, natural product chemistry. Non experts interested in aromatic and medicinal plant agriculture, transformation and commercialization will also find the content informative.

Medicinal and Environmental Chemistry: Experimental Advances and Simulations is a collection of topics that highlight the use of pharmaceutical chemistry to assess the environment or make drug design and chemical testing more environment friendly.

The eleven chapters included in the second part of this book set cover diverse topics, blending the fields of environmental chemistry and medicinal chemistry and have been authored by experts, scientists and academicians from renowned institutions. This part is more specialized in nature, focusing primarily on the effects of air pollution and water contamination on human health. Chapters covering pharmaceutical interventions and pollution control measures, respectively follow these initial topics.

Part II also features specialized topics that aim to address some unique challenges of the above mentioned problems including antibiotic pollution, pharmaceutical analysis of pollutants, chemosensors, biosteric modifications and new drug development strategies against SARS-CoV2.

Key Features:

1. 11 topics which blend environmental chemistry and medicinal chemistry

2. Contributions from more than 40 experts

3. Includes topics covering effects of air pollution on human health and disease

4. Includes specialized topics on pharmaceutical analysis in the environment, and modifications of compounds for pharmaceutical purposes

5. Bibliographic references

This reference is an essential source of information for readers and scholars involved in environmental chemistry, pollution management and pharmaceutical chemistry courses at graduate and undergraduate levels. Professionals and students involved in occupational medicine will also benefit from the wide range of topics covered.

Melanin is a biological molecule associated with pigmentation in humans and animals. However, melanin has been observed to have other functions such as neuroprotection and energy production. In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. Nine chapters explain the intrinsic biochemistry of melanin, comparisons with conventional energy producing and respiratory biomolecules, the property of melanin to transform light energy into chemical energy through the dissociation of the water molecule, and the theories of melanin based energy production in the nervous system, the cell nucleus, muscles and the eye, and the role the role of melanin in the context of ageing. The authors also delve into the possibility of melanin being the key molecule needed to spark life since its water dissociating property through the absorption of light energy emulates the role of chlorophyll, but unlike the latter, it is not limited to the plant cell environment. Hence, melanin is referred to as the master molecule which can provide a missing link to the biochemical processes behind the origin of life.

Melanin, the Master Molecule is an exciting reference for biochemists and laymen interested in the science of melanin and a new perspective on the origin of life as we know it.

The electrical response of cells to mechanical stimulus is known as mechanotransduction. This monograph is a summary of the mechanotransduction in musculoskeletal cells responsible for body tissue maintenance, support, cover and movement. While mechanotransduction is similar among these cells, there are also several important differences in mechanical parameters and cellular pathways characteristic to each cell type. Therefore, readers will have the opportunity to update their knowledge about the increasing volume of information on mechanotransduction in these cells gained from current research.

The book features a primer on general aspects of cellular biomechanics and the experimental methods and equipment commonly used for investigating cellular mechanotransduction in vitro in two dimensional cultures in which cells are adherent to plastic surfaces. Characteristic mechanotransduction pathways in mesenchymal stem cells (MSCs), chondrocytes, osteoblasts and fibroblasts are described in the accompanying chapters. Finally, a description of clinical implementation of mechanical stimulation is presented with emphasis on distraction osteogenesis, involving osteoblast stimulation, and skin stretching techniques based on fibroblast stimulation.

This monograph is a useful reference for readers involved in graduate courses or basic research in cell biology and musculoskeletal physiology.

For decades, scientific efforts have been made to understand obesity and related diseases such as type 2 diabetes and neurodegeneration, and their link with meta-inflammation. Adipose tissue is, at present, viewed as an endocrine organ with important biological effects on metabolism and inflammation, with a possible role in the pathogenesis of obesity-associated metabolic and inflammatory diseases. Chronic systemic low-grade inflammation has gained significant attention as the key player in the pathophysiology of obesity- and aging-associated diseases. Keeping view of this trend, Meta-Inflammation and Obesity offers readers state-of-the-art knowledge on this subject. Chapters cover special topics such as gender differences in obesity-related type 2 diabetes as the consequence of inflammatory response, insights into metabolic changes caused by excessive adipose tissue (which lead to abnormal brain metabolism, neuroinflammation, cognitive decline, development of type 3 diabetes), and the importance of inflammaging in the aging process. Graduate, postgraduate and Ph. D. candidates in medicine, pharmacy, and students of applied medicine, health care professionals as well as scientists involved in adipose tissue research, meta-inflammation analysis, obesity-related medical specialties will find this book a useful reference on the link between inflammation and obesity.

Metabolites of Medicinal Plants: Insightful Approaches provides a comprehensive exploration of the bioactive compounds found in medicinal plants and their pharmacological significance. The book covers key topics such as the economics of medicinal and anticancer plants, phytochemistry, therapeutic potential, and advanced applications like nanotechnology-based drug delivery systems and CRISPR-Cas techniques. It also examines the role of these plants in combating diseases like diabetes and metabolic syndrome and their role in traditional medicine systems. This resource is essential for students, researchers, and professionals in phytochemistry, pharmacology, drug discovery, and healthcare practices.

Key Features:

1. Wide range of topics from medicinal plant economics to pharmacological applications.

2. Latest discoveries in plant bioactive compounds and their therapeutic uses.

3. Novel drug delivery methods to enhance efficacy.

4. Linking genes to metabolites through advanced omics approaches.