Bentham Science Publishers

In this third year of the SARS-CoV-2 pandemic responsible for COVD-19 and related diseases worldwide, the scientific studies and reviews focused on this virus and its variants are still crucial. The third volume of the Coronaviruses series brings together some essential data regarding the origin, pathology and chemotherapeutic drugs to treat coronavirus infections. Contributions are written by experienced researchers with the goal of updating medical researchers and clinicians dealing with COVID-19 patients. It presents seven chapters covering a range of topics: (1) bat coronaviruses in the world, (2) hospital challenges during the COVID-19 pandemic, (3) the pro-inflammatory and thrombotic manifestations and the therapeutic options of Covid-19, (4) the common and rare dermatologic manifestations registered in COVID-19 patients, (5) the circulating biomarkers of cardiopulmonary disturbances in COVID-19, and (6) the aspects of pathology and pathogenesis of coronavirus infection

Students studying chemistry often struggle with the mole. Counting Moles provides an effective aid to learning by giving clear and confident presentation of the essentials of the mole concept needed by those starting chemistry courses. This user-friendly self-teach e-book is split into six chapters which sequentially introduce the ‘mole calculating frame' to help solve problems. Over 200 fully worked examples are given along with several hundred questions.

The mole concept is applied to topics such as relative atomic mass and relative formula mass, percentage composition, empirical and molecular formula. The book also covers concentration, its units, volumetric analysis and the relationship between volume, mass and moles of gases. Counting Moles culminates in you taking a Mole Driving Test. On passing this test, you are issued with a Counting Moles Driving License that will give you all the confidence required to correctly answer all mole calculations.

Craniofacial Disorders – Orofacial Features and Peculiarities in Dental Treatment presents detailed information about craniofacial disorders and their features.

The contents of the book cover craniofacial embryology, craniofacial genetics and teratology, craniofacial abnormalities (etiology, systemic involvement, and treatment methods and surgical steps required for complex dentomaxillofacial reconstruction for aesthetic or functional improvements.

This book is an easy-to-read handbook for clinical dentists who wish to enhance their knowledge on the subject and offer dental care for individuals affected by craniofacial disorders.

In the last two decades, many new fractional operators have appeared, often defined using integrals with special functions in the kernel as well as their extended or multivariable forms. Modern operators in fractional calculus have different properties which are comparable to those of classical operators. These have been intensively studied for modelling and analysing real-world phenomena. There is now a growing body of research on new methods to understand natural occurrences and tackle different problems.

This book presents ten reviews of recent fractional operators split over three sections:

1. Chaotic Systems and Control (covers the Caputo fractional derivative, and a chaotic fractional-order financial system)

2. Heat Conduction (covers the Duhamel theorem for time-dependent source terms, and the Cattaneo–Hristov model for oscillatory heat transfer)

3. Computational Methods and Their Illustrative Applications (covers mathematical analysis for understanding 5 real-word phenomena: HTLV-1 infection of CD4+ T-cells, traveling waves, rumor-spreading, biochemical reactions, and the computational fluid dynamics of a non-powered floating object navigating in an approach channel)

This volume is a resource for researchers in physics, biology, behavioral sciences, and mathematics who are interested in new applications of fractional calculus in the study of nonlinear phenomena.

Research demonstrates that even if empathy – the capacity to perceive or share emotions with other beings or objects – is not part of a person’s communication skill set, it can be taught. Empathy can, therefore be viewed as an acquired communication skill. Cultivating and practicing the skill of empathy among health care providers enhances the quality of care experienced by their patients which, in turn, can even improve work satisfaction for health care providers.

Many communication textbooks or manuals for care giving professions primarily focus on specific communication skills and techniques. Cultivating Empathy takes a different approach; the book sets empathy as the foundation of all therapeutic interactions and teaches the reader to learn the art of empathy by using constructive approaches and research findings from social sciences and neuroscience.

In this revised edition. The definition of empathy now incorporates more scientific evidence from the social neuroscience and a discussion of the benefits of positive psychology. The topic of substance use has been incorporated into the original content, with notes emphasizing on barriers to treatment and recommendations for therapeutic modalities that support recovery. The positive and negative effects of social media on empathic capacity are frankly discussed. Chapter Seven is completely new and heightens our understanding of the fact that trauma is prevalent and pervasive in society and has significant negative consequences. The reader is made aware that even though health professionals have frequent contact with people who have a history of violence, many of them are not trained or adequately prepared to discuss trauma with their clients. Therefore, crucial components of a trauma-sensitive practice and trauma-informed approaches are promoted to treat the devastating effects of adversity. There is also a cost to caring for others and being empathetic. That is why Chapter Eight of this book specifically explores the trauma and emotional stress associated with being a caregiver.

Cultivating Empathy is perfect for any student or practicing health care professional who has felt that there was an absence of rapport when interacting with clients or patients and their families. Real case narratives, dynamic interactive exercises and simulation techniques are also provided in this text to assist helpers to learn how to be more empathetic. Readers will gain awareness about human and emotional aspects of patient care, which will hopefully make a positive contribution to their professional practice.

Without a thorough understanding of culture and its nuances on part of the mental health service providers, alienation, stigma, and culturally based impediments rule. While concerns for diversity have been raised on numerous occasions, with increasing frequency over the past four decades, little progress has been made in implementing such concerns in clinical practice. Over two-thirds of Americans receive treatment for depression, anxiety, substance abuse, and related disorders. Comorbidity is rarely diagnosed. These trends are greatly exacerbated among members of ethnic, cultural, and linguistic minority groups. The authors contributing to this volume share their clinical acumen and experiences, rooted in their evidence-based research. Their purpose is to bring issues attending assessment and treatment of ethnic minority clientele closer to the fore. Some of the leading authors on the topic, in psychology and social work, present their well earned clinical and research experiences in this volume. Case studies are presented which are instructive and intriguing, bringing together the richness of a multidisciplinary approach to the topic.

Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. FDDFs were initially available as orodispersible tablets, and later, as orodipsersible films for treating specific populations (pediatrics, geriatrics, and psychiatric patients). Granules, pellets and mini tablets are among latest additions to these dosage forms, which are still in the development pipeline. As drug delivery systems, FDDFs enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption. With time, FDDF have evolved to deliver drugs in a sustained and controlled manner. Their current market and application is increasing in demands with advances in age adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability.

This book presents detailed information about FDDFs from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.

Current Aging Science publishes frontier review and experimental articles in all areas of aging and age-related research that may influence longevity. This multidisciplinary journal will help in understanding the biology and mechanism of aging, genetics, and pathogenesis, intervention of normal aging process, and preventive strategies of age-related disorders.  The scope of this journal includes psychological, sociological, biochemical and clinical approaches related to aging, elderly patients and the relevant clinical treatment. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, clinical, molecular, and animal models, including lower organism models (e.g., yeast, Caenorhabditis elegans and Drosophila). In addition to the effect of aging on integrated systems, the journal also covers original articles on recent research in fast emerging areas of adult stem cells, brain imaging, calorie restriction, immunosenescence, molecular diagnostics, pharmacology and clinical aspects of aging. Manuscripts are encouraged that relate to developmental programming of aging and the synergistic mechanism of aging with cardiovascular diseases, obesity and neurodegenerative disorders.
Book reviews, meeting reports, letters-to-the-editor and drug clinical trial studies are also published. The journal is an essential reading for researchers, educators and physicians having interest in aging, age-related dementia and Alzheimer's disease, and longevity. Current Aging Science provides comprehensive coverage of the current state of the art research on aging for gerontologists, neuroscientists, clinicians, health science planners, granting agencies, and pharmaceutical scientists.
Current Aging Science is an international, peer-reviewed journal on all aspects of aging and age-related research, published tri-annually (print & online) by Bentham Science Publishers.

• Artificial Intelligence in Polymers
• Biopolymers and Sustainable Polymers
• Data Mining Techniques
• Industrial Applications of Polymers
• Machine Learning Applications
• Modeling and Simulation
• Polymer Blends and Alloys
• Polymer Coatings and Adhesives
• Polymer Composites and Nanocomposites
• Polymer Degradation and Stability
• Polymer Electronics and Photonics
• Polymer Processing and Engineering
• Polymer Rheology and Mechanics
• Polymer Surfaces and Interfaces
• Polymer Synthesis and Characterization
• Polymers for Energy Storage and Conversion
• Polymers in Medicine and Biotechnology
• Recycling and Environmental Impact of Polymers
• Smart Polymers and Responsive Materials

Current Cancer Biomarkers is a comprehensive review on the status of biological markers for various types of cancer. It aims to update readers on current developments on the subject. The contents are divided into 5 sections covering a wide range of biomarkers and their diagnostic applications. The range of tumour biomarkers referenced here gives insights into molecular mechanisms behind cancer, including initiation, development, progression, prognosis, response to the therapeutic modalities, recurrence, and point-of-care application to detect cancer. Key features - Introduction of the basic features of cancer markers - Comprehensive and updated coverage of potential and effective biomarkers including genomic, epigenomic, transcriptomic, proteomic, cellular and morphologic factors - Information on biomarkers in many types of cancers including breast cancer, colorectal cancer, skin cancer, leukemia, liver cancer and prostate cancer - Applications of biomarkers in cancer diagnosis - Structured contents with easy-to-understand sections and headings - References for advanced readers The updated information about different aspects of cancer markers in the experimental and clinical setting will enrich the reader's understanding of the disease. The information serves as a resource to help in better management of cancer patients and understanding cancer biology when planning medical research projects. The book is intended as a reference for a diverse audience: biomedical science students, medical students, academics, researchers, clinicians and multidisciplinary teams involved in cancer management and research.

• Advanced Catalyst Synthesis
• Asymmetric Catalysis
• Biocatalysis
• Catalysis and Reaction Engineering
• Catalysis for Sustainable Energy
• Catalyst Deactivation and Regeneration
• Catalytic biomass conversion
• Catalytic CO2 utilization
• Catalytic Materials
• Catalytic Reactors
• Catalytic Waste Valorization
• Electrocatalysis
• Environmental catalysis
• Heterogeneous Catalysis
• Homogeneous Catalysis
• Nanoparticle Catalysts
• Nanostructured Catalysts
• Photocatalysis
• Plasma-Catalysis
• Sustainable Catalysis

• Analytical tools
• Bacterial and viral cell-based chemistry
• Biological fluorescence
• Biologically active natural products
• Biomimetic synthesis
• Bioorganic and bioinorganic chemistry
• Bioorthogonal Chemistry
• Bioorthogonal reactions
• Biophysical Chemistry
• Biosynthetic engineering
• Cell signaling chemistry
• Chemical Biology in Agriculture
• Chemical Biology of Disease
• Chemical Biology of Lipids and Membranes
• Chemical Biology of Nucleic Acids
• Chemical Genetics
• Chemical Systems Biology
• Chemical Tools for Biology
• Chemical Ecology
• Chemical Imaging
• Chemical Informatics
• Chemical Mechanisms of Biological Systems
• Chemical Synthesis
• Combinatorial chemistry
• Directed evolution
• Enzymology
• Glycobiology
• Kinases
• Macromolecules
• Mechanistic biology
• Medicinal Chemistry
• Metabolomics
• Metagenomics
• Metal ions in biological systems
• Metalloenzymes
• Molecular imaging
• Nanobiotechnology
• Natural product synthesis
• Peptide synthesis
• Plant cell-based chemistry
• Proteomics
• Receptor chemistry
• Solid-phase biomolecular synthesis
• Structural Biology
• Synthetic biology
• Unnatural biomolecular analogs

1. AI/ML algorithms for hit identification, optimization, and target prediction
2. Deep learning, generative models for de novo drug design
3. Multi-omics integration, pharmacogenomics and AI for target identification
4. AI-enhanced molecular dynamics and binding free energy calculations
5. Structure- and ligand-based drug design
6. AI-assisted repurposing of existing drugs and natural products

• Cosmetic material research and characterization
• Cosmetic and Cosmeceutical formulation development
• Characterization and evaluations
• In vitro and in vivo safety in humans
• Efficacy of cosmetics and cosmeceuticals
• Toxicological studies in various animal models
• Topical products intended for Skin, nails and hair
• Analytical techniques involved in cosmetic and cosmeceutical product formulations and analysis
• Cosmetic Surgery and Dentistry
• Skin physiology and pharmacology
• Aesthetic and rejuvenation research
• Topical and transdermal testing
• Physical chemistry and technology of emulsion and dispersed systems, theory and application of surfactants
• Olfactory research
• Antioxidants
• Natural products

The rise in the incidence of infections is caused by multi drug resistant (MDR) bacteria, it is essential to elucidate the basic mechanism of antibiotic resistance to discover effective methods for diagnosis and treatment of infections.

The use of pathogen-specific probes offers a faster alternative for pathogen detection and could improve the diagnosis of infection. High resolution melting analysis techniques are useful for the detection of multi drug resistant pathogens. Rational Structural Based Drug Design is a common method to identify a lead compound and take it forward for further developments.

This book provides information about recent strategies involved in the diagnosis and treatment of infections caused by MDR bacteria. The volume covers the use of molecular probes for the quantification of pathogenic bacteria, along with other techniques mentioned above.

Chapters also cover the use of identification of novel drug targets from the Lipid A biosynthesis and also from quorum sensing mediated biofilm formation in MDR bacteria. Chapters also cover herbal alternatives for the treatment of MDR bacteria like the use of Cassia aungustifolia in treatment of various diseases. The reference is suitable for biomedical students, cellular and molecular biologists.

One of the most extraordinary characteristics of Mycobacterium tuberculosis infection is its capacity to remain within the host's tissues for a long period of time. There is an enormous reservoir of persons latently infected with tuberculosis (LTBI) estimated at about a third of the world's population. From this reservoir arise about 10 million new cases of active TB and more than two million deaths occur annually. Current Diagnosis of Infant Tuberculosis Infection covers problems concerning the diagnosis of LTBI, giving an overview of commercially available options and, unlike most reviews on this subject, also points out some tools currently under development. The Ebook provides comprehensive understandable, practice-oriented information on this subject, while keeping frontier research developments in consideration. It serves as an update to readers from universities to the research center and hospital staff - as well as a guide for helping clinicians to improve their diagnostic skills regarding TB infections in an endemic country (such as Brazil).