Bentham Science Publishers
Bentham Science Publishers is a major publisher of more than 100 peer-reviewed science, technology and medical (STM) journals, along with a rapidly growing collection of eBooks. Since 1993, Bentham Science Publishers has been catering to the information needs of the pharmaceutical, engineering, biomedical and medical research community.1251 - 1300 of 1750 results
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Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics
Genetic disorders have been the focus of scientists for a long time. The emergence of next-generation sequencing techniques has ushered a new era in genetics and several developments have occurred in human genetics. The scientific perspective has also been widened with omics technologies that allow researchers to analyze genetic sequences and their expression products. An integrated approach is being used not only for diagnosis but also for disease management and therapeutic purposes.
This book highlights emerging areas of omics technology and its application in the diagnosis and management of human genetic disorders. The book covers three areas of research and implementation:
- Diagnosis (covering conventional strategies to next-generation platforms). This section focuses on the role of in silico analysis, databases and multi-omics of single-cell which will help in designing better management strategies.
- Disease Management and therapeutic interventions. This section starts with genetic counselling and progresses to more specific techniques such as pharmacogenomics and personalized medicine, gene editing techniques and their applications in gene therapies and regenerative medicine.
- Case studies. This section discusses the applications and success of all the above-mentioned strategies on selected human disorders.
This book serves as a handy reference for students and academics studying advanced omics techniques in biochemistry and molecular genetics as part of courses in life sciences, pharmacology and medicine.
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Omics and Plant Abiotic Stress Tolerance
Multiple biotic and abiotic environmental factors may constitute stresses that affect plant growth and yield in crop species. Advances in plant physiology, genetics, and molecular biology have greatly improved our understanding of plant responses to stresses. This book details on technologies that have emerged during the past decade and have been useful in studying the multigenicity of the plant abiotic stress response. Upstream molecular mechanisms are involved in the plant response to abiotic stress, above all in the regulation of timings and amount of specific stress responses. Post-transcriptional mechanisms based on alternative splicing and RNA processing, as well as RNA silencing define the actual transcriptome supporting the stress response. Beyond protein phosphorylation, other post-translational modifications like ubiquitination and sumoylation regulate the activation of pre-existing molecules to ensure a prompt response to stress factors.
The text in this book deals with the importance of -omics approaches like Genomics, Metabolomics and Proteomics in abiotic stress tolerance. Large scale analytical approaches provide detailed information about the structure and complexity of signaling networks, identify subsets of genes or activities that are correlated to given stress factors and reveal unexpected or previously uncharacterized biochemical interactions.
To the best of our knowledge no book on -Omics studies in relation to Plant Abiotic Stress Tolerance is available in the market. This book should therefore be a valuable asset for the readers.
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On Generalized Growth rates of Integer Translated Entire and Meromorphic Functions
The theory of entire and meromorphic functions is a very important area of complex analysis. This monograph aims to expand the discussion about some growth properties of integer translated composite entire and meromorphic functions on the basis of their (p,q,t)L -order and (p,q,t)L -type.
This book presents six chapters. Chapter 1 introduces the reader to the preliminary definitions and notations. Chapter 2 and Chapter 3 discuss some results related to (p; q; t) L-th order and (p; q; t)L-th lower order of composite entire and meromorphic functions on the basis of their integer translation. Chapter 4 establishes some relations of integer translated composite entire and meromorphic functions based on their (p; q; t) L-th type and (p; q; t) L-th weak type. Chapter 5 deals with some results about (p; q; t) L-th order and (p; q; t) L-th type of composite entire and meromorphic functions on the basis of their integer translation. Chapter 6 focuses on some results about (p; q; t) L-th order and (p; q; t) L-th type of composite entire and meromorphic functions on the basis of their integer translation.
This monograph will be very helpful for postgraduates, researchers, and faculty members interested in value distribution theorems in complex mathematical analysis.
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On-Chip Pretreatment of Whole Blood by Using MEMS Technology
The Microfabrication technology has stimulated a plurality of lab-on-a-chip research for biomedical researchers and health care practitioners to manipulate and analyze complex biological fluids at the nano and microliter scale. Specifically, various miniaturized diagnostic devices have been developed for blood sample detection, which can increase diagnostic capacity significantly by enabling rapid, point-of-care chemical analysis. Recently, more and more researchers are paying attention to on-chip whole blood sample pretreatment, which is the focus of this eBook, aiming to form real Micro Total Analysis Systems (uTAS) for whole blood analysis by integrating blood sample pre-treatment and detection together.
The eBook consists of six chapters. Chapter 1 gives a brief introduction on the background of whole blood and the concept of µTAS, followed by a summary of specific microfluidic chips for whole blood pretreatment. Chapter 2 firstly reviews microfluidic chips for plasma isolation from whole blood samples with various methodologies (i.e., microfiltration, microcentrifugation, ultrasound, Zweifach–Fung effect and capillary effect). Then two examples using the plasma skimming effect and crossflow filtration respectively are discussed in detail. Chapter 3 firstly reviews microfluidic devices for blood cell filtrating, sorting and collection. Sorting methods such as size filtration, optical and magnetic manipulation, affinity separation, dielectrophoretic manipulation are covered and compared. Then a case study using crossflow filtration is analyzed in detail. Chapter 4 firstly reviews reported microfluidic devices for blood cell lysis in which mechanical lysis, sonication lysis, thermal lysis, electrical lysis, chemical lysis and optical lysis are covered. And then a cell lysis microchip using chemical agents for cell lysis is chosen as an example for further concept demonstration. Chapter 5 firstly reviews microfluidic devices for DNA extraction and purification by comparing reported methods of solid phase extraction, solid phase reversible immobilization and liquid/liquid extraction. And then two microchips with different solid phase matrixes are used for demonstration of chip based DNA extraction. Chapter 6 firstly reviews current integrated microfluidic platforms for blood pretreatment, followed by a case study.
Both fundamental analysis and specific applications are presented in this eBook, which is written for researchers, engineers, and advanced students who have research interest in whole blood pretreatment and miniaturized techniques.
We would like to express our appreciation to Bentham Science Publishers and their team members.
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One-Dimensional Transient Flow in Pipelines Modelling and Simulation
This book presents numerical computational fluid dynamics (CFD) solutions for studying the effect of fluid-structure interaction (FSI) on evaluation of pressure waves in pipelines with cavitation. The authors develop a uniform one-dimensional model using coupled models. These models consider unsteady friction (UF), Poisson coupling, axial vibration (junction coupling), gas release and viscoelasticity. The authors consider two cases: elastic pipelines and viscoelastic (VE) pipelines.
The book starts with a detailed literature review on the relevant methods for calculating transient fluid flow, followed by chapters that explain the mathematical development for calculations and the numerical steps for water hammer and transient cavitation. The concluding chapters present the results for the two pipeline cases.
The book is presented in simple language intended for engineering students who want to understand CFD simulations for transient flow in pipelines. Equations are explained in simple steps for easy understanding, and concepts are illustrated with detailed diagrams. The information and the codes demonstrated in the book will equip readers with the knowledge to study hydraulic problems where transients are caused by pump starting, stopping and failure.
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Online Health Forums and Services: Benefits, Risks and Perspectives
The internet provides a major source of exchanging health information through online portals and new media. Internet users can access health sites and online forums to obtain health information. In turn, these information sources act as a catalyst for wellbeing and improving personal health care behaviors and routines. Competent health institutions encourage the development of these individual behaviors that enable individuals to increase health empowerment and to take responsibility for their own health needs, diagnosis and treatment.
Online Health Forums and Services: Benefits, Risks and Perspectives is an investigation of the use of online health forums and services. The author first introduces the reader to the theories that define online social behaviors in terms of health care services. The chapters following this introduction attempt to account for the variations in online health care portal use and to what extent does social networking induce variations in health behaviors grounded in theory. A summary of media used for affecting health behavior change is also provided along with a discussion of the socioeconomic attributes of the individuals most likely to be affected in terms of their health behaviors.
The book provides a comprehensive perspective that links the aspects of the micro-level use of the Internet for health purposes (accessing health related websites, participation in health forums and networking sites) to the macro level practices of telemedicine. Readers will be able to understand the social and health characteristics of the different groups of patients and estimate the extent to which individuals in need of health and medical information are taking advantage of the availability of information and communication platforms to improve their health, or if they are being left behind. This is a timely reference for healthcare professionals, researchers and consultants involved in digital health care initiatives and public health administration who are seeking information about how access to online health information can influence lifestyles in a way that impacts human behavior in a positive, meaningful way.
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Oocyte Maturation and Fertilization: A Long History for a Short Event
Events of reproduction occurring from meiotic resumption of the immature oocyte up to its exit from the second meiotic block following activation will be revealed. Morphological modifications of the oocyte during maturation will be related to signal transduction mechanisms involving primary or secondary messengers. A detailed view will be addressed to genetic and epigenetic control of oocyte maturation. At fertilization, reciprocal gamete activation and novel knowledge related to sperm factor and cascade mechanisms occurring in the oocyte will be focused. A detailed description of ion currents occurring during fertilization will depict another point of view of oocyte activation mechanisms, further supporting for their complexity.
Finally, all basic information related to this short time lapse will be considered in relation to clinical application of assisted reproductive technologies. New frontiers, such as stem cells and cloning technologies, will be analyzed and future applications and improvements will be hypothesised.
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Open Quantum Physics and Environmental Heat Conversion into Usable Energy: Volume 2
The second volume of this book series presents a foundation for describing electron-field interactions, the basic elements involved in open quantum theory, the dissipative couplings of the active elements, the quantum injection dot electrons and coherent electromagnetic fields produced by crystal lattice vibrations. A microscopic description of the systems of interest is used to explain a number of structural models that describe electron arrangement and mechanics in such systems. The explanation of these models depends on a number of numerical parameters and calculations which have been explicitly discussed in detail. Readers will gain a better understanding of open quantum systems and energy conversion in semiconductor devices. Theoretical calculations presented in this book can also be compared with experimental data from prior experiments. The volume is also supplemented by an adequate bibliography which provides useful references.
This book is a handy text on advanced quantum theory for advanced physics and electronics students and researchers.
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Open Quantum Physics and Environmental Heat Conversion into Usable Energy: Volume 3
This volume presents a clear understanding of the quantum mechanics of particles with reference to the current understanding of theory of relativity, gravitation, and electromagnetism, including essential phenomena as spin, the graviton spin, black holes, and the quantum particle states in the extreme conditions of a black hole formation, and of the Schwarzschild boundary. The reader is introduced to the recent theory of the quantum particle dynamics as a distribution of matter propagating with the velocity of the waves. The text describes this distribution by a Fourier space-time series expansion, which we call the wave function. The subsequent chapters delve into the mechanics of quantum particles in a gravitational field, charged particles in a gravitational field and finally, the least action and matter-field dynamics in a gravitational field. The book also explains important rules in quantum mechanics such as the mass quantization rule, Dirac's formulation of the general theory of relativity, electromagnetic field theory, quantum particle interactions and more. The volume serves as a concise introduction to the complex topic of quantum particle mechanics for scholars involved in advanced physics courses.
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Open Quantum Physics and Environmental Heat Conversion into Usable Energy: Volume 4
Open Quantum Physics and Environmental Heat Conversion into Usable Energy - Vol. 4 explores the intricate relationship between quantum mechanics, relativity, gravitation, and electromagnetism, offering insights into the dynamics of quantum particles in various fields. The book covers key phenomena such as spin, graviton spin, black holes, and quantum states in extreme conditions, including black hole formation. It explains how quantum particles behave as distributions of matter, using wave functions to describe their propagation. Further, it examines electromagnetic and gravitational field interactions, quantum particle transitions, Dirac's formalism of general relativity, and their applications in quantum electrodynamics and unified field theory.
Key Features:
- Detailed explanation of quantum particle dynamics and wave function theory.
- Discussion of quantum particle transitions and spinor fields.
- Exploration of black hole dynamics and gravitational wave interactions.
- Comprehensive coverage of unified field theory, integrating electromagnetism and gravity.
- Applications to quantum electrodynamics and particle collisions.
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Opportunities And Limitations For Biotechnology Innovation in Brazil
Brazil has emerged as a significant financial and industrial power in recent times. Brazil is poised to become a significant player in the field of biotechnology, internationally, by taking advantage of circumstances not available in other countries, particularly its native biodiversity. This will, in turn, have an effect on commercial and entrepreneurial opportunities in the region.
Topics covered in this text include adjustments that must be made in the regulatory framework to assure the success of business investment. This investment is crucial for training R&D scientists and developing new technologies. The book also covers a debate on transgenic plants which had political ramifications in the region and slowed the adoption rate of genetically modified organisms by almost a decade. The opportunities for commercialization of recombinant DNA technologies in the country are also presented.
Opportunities and Limitations For Biotechnology Innovation In Brazil presents a concise overview of the biotechnology industry in Brazil and will be of great interest to a wide range of readers including researchers, biotechnology graduates, as well as both local and international investors.
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Opportunities for Biotechnology Research and Entrepreneurship
Opportunities for Biotechnology Research and Entrepreneurship explores the intersection of scientific innovation and entrepreneurial endeavors in the field of biotechnology. With a focus on addressing real-world challenges and creating transformative solutions, this book offers valuable insights into the diverse applications of biotechnology across ecology, food, industrial, and medical sciences. Comprising 20 chapters, this edited volume brings together contributions from experts around the globe, offering a comprehensive overview of emerging research trends and techniques. Each chapter provides necessary background information and presents current and future applications of biotechnology, making it an ideal resource for students, researchers, and industry professionals. Key features include global perspectives, concise summaries tailored for easy understanding, and updated data accompanied by illustrations and flow charts. Whether exploring environmental sustainability, enhancing food security, optimizing industrial processes, or advancing medical treatments, this book serves as a valuable reference for those interested in the dynamic field of biotechnology.
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Optical Coherence Tomography Angiography for Choroidal and Vitreoretinal Disorders - Part 1
This handbook covers Optical Coherence Tomography Angiography (OCT-A) with a specific focus on choroidal and vitreoretinal disorders. It serves as an invaluable resource for teaching and aiding daily clinical decision-making in the field. Book chapters dissect the fundamentals of angiography through OCT, offering guidance on OCT-A and insights into macular perfusional findings across various vitreoretinal and choroidal pathologies. From diabetic retinopathy to autoimmune diseases and neovascularization, the book addresses prevalent vascular entities encountered in routine practice. Furthermore, it explores innovative approaches, including antivascular endothelial growth factor molecules and extended-release delivery devices, contributing significantly to the diagnostic and decision-making processes in clinical and surgical retina care. Each chapter is contributed by experts in the relevant subspecialty.
Key Features:
Practical, patient-centered guide emphasizing a clinical approach.
Demonstrative clinical cases for enhanced understanding.
Evaluation of perfusional indices using noninvasive and noncontact imaging techniques.
High histopathological correlation of structural tissue characterization with microvascular evaluation.
Exploration of new perfusion concepts and their role in disease pathogenesis.
Part 1 of the book focuses on OCT-A principles and applications in ophthalmology. It covers the basics of OCT-A, its contributions to eye disease study and treatment, and a comparative analysis with OCT for choroidal and vitreoretinal diseases. Additional information on nomenclature, normative datasets, and data analysis, presenting indices in different eye conditions is also presented. The emphasis is on macular perfusion in surgically resolved myopic foveoretinal detachment, postoperative evaluation in retinal detachment, and long-term analysis in diabetic retinopathy.
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Optical Coherence Tomography Angiography for Choroidal and Vitreoretinal Disorders – Part 2
This handbook covers Optical Coherence Tomography Angiography (OCT-A) with a specific focus on choroidal and vitreoretinal disorders. It serves as an invaluable resource for teaching and aiding daily clinical decision-making in the field. Book chapters dissect the fundamentals of angiography through OCT, offering guidance on OCT-A and insights into macular perfusional findings across various vitreoretinal and choroidal pathologies. From diabetic retinopathy to autoimmune diseases and neovascularization, the book addresses prevalent vascular entities encountered in routine practice. Furthermore, it explores innovative approaches, including antivascular endothelial growth factor molecules and extended-release delivery devices, contributing significantly to the diagnostic and decision-making processes in clinical and surgical retina care. Each chapter is contributed by experts in the relevant subspecialty. Key Features: Practical, patient-centered guide emphasizing a clinical approach. Demonstrative clinical cases for enhanced understanding. Evaluation of perfusional indices using noninvasive and noncontact imaging techniques. High histopathological correlation of structural tissue characterization with microvascular evaluation. Exploration of new perfusion concepts and their role in disease pathogenesis. Part 2 covers advanced topics in OCT-A for choroidal and vitreoretinal disorders. Chapters explore macular perfusional repercussions in obstructive venous vascular phenomena, OCT-A findings in retinal infarction, and the role of macular perfusion in myopic macular traction maculopathy. Further discussions include postoperative perfusional findings in vitreoretinopathy, distinctions in choroidal vasculopathies, and the application of OCT-A in managing pathological choroidal neovascularization. The part concludes with a review of postoperative membrane formation, the usefulness of OCT-A in neurodegenerative diseases, and the evaluation of arterial occlusions and choroidal neovascularization management.
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Optimality Conditions in Vector Optimization
Vector optimization is continuously needed in several science fields, particularly in economy, business, engineering, physics and mathematics. The evolution of these fields depends, in part, on the improvements in vector optimization in mathematical programming. The aim of this Ebook is to present the latest developments in vector optimization. The contributions have been written by some of the most eminent researchers in this field of mathematical programming. The Ebook is considered essential for researchers and students in this field.
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Oral Infections and Cardiovascular Disease
This book provides a comprehensive overview of current knowledge about research in oral infections and their association with cardiovascular diseases. Several epidemiological, clinical and other scientific aspects are covered in this book through the work of medical experts.
The detailed accounts in this book are of great value to readers in the scientific community, practitioners, teachers and students in relevant fields, and health-care planners.
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Ordinary Differential Equations and Applications I: With Maple Examples
Ordinary Differential Equations and Applications I: with Maple Examples blends the theory and practical applications of Ordinary Differential Equations (ODEs) with real-world examples, using Maple and MapleSim software. It covers fundamental ODE concepts, from first-order equations to more advanced topics like the Laplace and Mellin transforms, Fourier series, and power series solutions. The book includes detailed Maple examples demonstrating symbolic solutions, 2D and 3D plotting, and animated solution paths.
Designed for undergraduate and postgraduate students in mathematics, physics, engineering, and other fields, it is also a valuable resource for professionals. The book addresses various applications in biology, economics, chemistry, and medicine.
Key Features:
- In-depth coverage of ODEs with real-world applications.
- Maple examples for symbolic solutions, plotting, and animations.
- Exploration of Laplace, Mellin, and Fourier series methods.
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Ordinary Differential Equations and Applications II: with Maple Illustrations
Ordinary Differential Equations and Applications II: With Maple Illustrations integrates fundamental theories of Ordinary Differential Equations (ODEs) with practical applications and Maple-based solutions. This comprehensive textbook covers vector-valued differential equations, matrix solutions, stability methods, and periodic systems. Using Maple and MapleSim software, readers learn symbolic solutions, plotting techniques, 2D/3D animation for ODE problems, and simulations for engineering systems.
This book is ideal for undergraduate and postgraduate students in mathematics, physics, economics, and engineering, as well as researchers and professionals needing advanced applications of ODEs. Key Features:
- Comprehensive introduction to ODE concepts and real-life applications
- Solutions for initial value problems using Maple and MapleSim software
- Analysis of stability using Routh-Hurwitz and Lyapunov methods
- Models of neural firing, avian influenza, and biological populations
- Practical guidance on MapleSim for multi-domain simulations, code generation, and Monte Carlo simulation
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Organ-specific Parasites in Cattle
Organ-specific Parasites in Cattle explores parasitic diseases affecting various organs in cattle, offering a deep dive into their diagnosis, treatment, and prevention. The book provides valuable insights into the etiology, symptoms, and pathophysiology of parasitic infections across critical organ systems, including the gastrointestinal tract, urogenital system, circulatory system, and more. With an emphasis on the latest research, it highlights advanced diagnostics, histopathological techniques, and the development of antiparasitic drugs and vaccines.
Readers will gain a thorough understanding of host-parasite interactions, resistance mechanisms, and effective control strategies, all presented with detailed explanations and visual aids. Designed to serve as a key reference, this book is essential for students, researchers, veterinary practitioners, and academicians aiming to deepen their knowledge in parasitology and animal health.
Key Features:
- Comprehensive coverage of organ-specific parasitic diseases in cattle
- Detailed focus on diagnosis, treatment, and preventive strategies
- Latest advancements in anti-parasitic drugs and vaccines
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Organic Spectroscopy Technology and Applications
Organic Spectroscopy: Technology and Applications is an essential guide to the principles and practices of spectroscopy in organic chemistry. This comprehensive text covers the fundamentals of the electromagnetic spectrum, UV-visible, infrared (IR), Raman, nuclear magnetic resonance (NMR), and mass spectrometry, providing a structured approach to understanding each technique`s role in molecular analysis. Designed for students and professionals alike, the book emphasizes problem-solving and structural analysis, offering a methodical progression through each technique to build practical expertise. Illustrated with detailed diagrams and real-world spectra, the text also includes solved examples to reinforce learning and enhance application skills.
Key Features:
- Comprehensive coverage of core spectroscopy techniques: UV-visible, IR, Raman, NMR, and mass spectrometry.
- Step-by-step explanations and problem-solving techniques for structural analysis.
- Numerous illustrations and spectra for visual learning.
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Organizational Management: Case Studies for Graduate Students
This eBook presents two case studies of two organizations operating in Lebanon. The author has examined the organizational management practices of these two companies and then proposed solutions for each identified problem. The case studies represent an electromechanical company working in the construction field and a retail company that sells different product lines. This handbook is suitable for readers who are familiar with concepts in organizational management and development. Engineers working in the construction field may also find this book helpful in improving their managerial expertise and for understanding the way different departments within a company work together.
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Organoid Technology: Disease Modelling, Drug Discovery, and Personalized Medicine
Organoid Technology: Disease Modelling, Drug Discovery, and Personalized Medicine covers organoid technology emerging as a transformative platform in biomedical research. Chapters explain in detail the physiologically relevant in vitro 3D models that closely mimic human tissues and organs. This book provides a comprehensive overview of the development, application, and future potential of organoids in modern life sciences. It highlights the critical applications in disease modeling, regenerative medicine, and high-throughput drug screening.
Key Features:
Covers organ-specific organoid development and bioengineering methods
Discusses integration with emerging technologies such as nanotechnology
Includes insights into personalized medicine using patient-derived organoids
Covers details about the current regulatory and ethical landscapes in organoids-based research.
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Organoselenium Chemistry: Between Synthesis and Biochemistry
The use of organoselenium reagents as catalysts is a common thread that runs through the chapters of this book, introducing important aspects of the modern organoselenium chemistry: organocatalysis, green chemistry, bioinspiration, antioxidant activity. The eBook covers the most recent developments in the classical synthetic application of organoselenium reagents such as electrophilic, nucleophilic and free radical reagents. The volume also features a discussion on the synthesis and the synthetic applications of some emerging classes of selenium compounds such as hypervalent selenium species and selenoamides, and also addresses some biological aspects such as the antimicrobial activity of organoselenium derivatives and the biochemistry of selenoproteins. A number of eminent scientists from different research groups were involved in the preparation of the 13 chapters of the book, making Organoselenium Chemistry: Between Synthesis and Biochemistry an excellent reference about selenium chemistry for researchers and graduate students in the field of selenium chemistry.
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Orofacial and Systemic Features of Thalassemia Major: Management, and Prevention with Reference to Populations in the Arabian Gulf
Thalassemia is one of the most common genetic diseases in the world. It has a relatively higher incidence in Mediterranean and Middle Eastern countries and presents a major public health and social challenge. This monograph updates the reader on the dental and orofacial characteristics of thalassemia major in Arab populations. Since very few detailed studies on these topics among Arabs have been published, the monograph attempts to bridge the knowledge gap in this area. Clinical, radiographic and odontometric features of the typical thalassemia major patient are clearly described in this book.
Key Features
- Provides a ready reference for dental and orofacial features in thalassemia major including a review of appropriate dental care
- Covers the pathogenesis, systemic complications, morbidity and mortality, management, and prevention of thalassemia major.
- Provides guidelines for optimal dental care.
- Covers special topics such as epidemiology, consanguinity, hematologic diagnosis, genetic testing, literature review, diet and nutrition, cost of treatment, and prevention
- Includes colored photographs, radiographs, drawings, tables, and 2 plates to illustrate examples and information
- Provides references for further reading
This monograph is a handy reference for medical and dental students, and caregivers on the subject of clinical dentistry in thalassemia patients.
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Orthodontic Biomechanics: Treatment of Complex Cases Using Clear Aligner
Recent Advances in Dentistry: Volume 1
Recent Advances in Dentistry is a monographic series focused on new developments in the field of dental medicine. The scope of the book series covers all aspects of the field including orthodontics, dental surgery, prosthodontics, forensic dentistry, evidence based medicine and much more. Each volume of the series is themed around a specialty area in dentistry and brings together contributions written and reviewed by professional experts. The book series is essential reading to dental residents in training as well as biomedical researchers.
Orthodontic Biomechanics describes the mechanics behind the treatment of complex orthodontic cases using clear aligners. The volume explains a variety of complex malocclusions including increased teeth crowding, spacing, overjet, overbite, open bite, major jaw discrepancies, underbite and much more. Simplified treatment planning methods based on thorough diagnoses have also been devised by the authors for the benefit of the readers. Shortening orthodontic treatment time by careful diagnosis, planning based on understanding of orthodontic biomechanics is also discussed in addition to comparisons of jaw cases where surgery is more useful.
Orthodontic Biomechanics is a useful guide for the use of clear aligners in a wide array of cases encountered by orthodontists in their daily dental practice.
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Orthodontic Treatment of Class III Malocclusion
"Orthodontic Treatment of Class III Malocclusion is a clinical textbook which highlights both research findings as well as clinical treatment of patients with Class III malocclusions. The volume equips readers with a critical review of present information about 1) the craniofacial biology behind various treatment strategies, 2) Diagnosis and treatment planning in both growing and non-growing Class III patients and 3) Contemporary orthodontic appliances using implants and miniscrews.
The book is divided into sections proving evidence-based research on the following aspects of Class III malocclusions: the genetic and epigenetic factors contemporary diagnosis and treatment planning for patients early treatment of Class III problems treatment of Class III problems in the adolescents surgical treatment of adult Class III patients treatment of Class III problems in patients with craniofacial anomalies
Orthodontic Treatment of Class III Malocclusion will empower clinicians with a sound knowledge about rationale for using certain treatment modalities and will help both general practitioners and specialists such as pediatric dentists and orthodontists to use this information for their daily practice."
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Orthogonal Frequency Division Multiplexing with Diversity for Future Wireless Systems
The book examines several aspects of Orthogonal Frequency Division Multiplexing (OFDM) employing linear diversity techniques such as inter-carrier interference, bit error rate, peak to average power and inter-block interference. It should be a useful reference for readers interested in modern wireless communication systems.
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Osteoporosis, Osteoarthritis and Rheumatoid Arthritis: An Agonizing Skeletal Triad
This comprehensive compendium unravels the intricacies of three common and daunting skeletal disorders: osteoporosis, osteoarthritis, and rheumatoid arthritis. These ailments afflict people across all age groups, demanding a deeper understanding of their diagnostic, prognostic, preventive, and therapeutic dimensions. It presents seven key topics written by medical experts that explore research on these diseases: Chronic Lung Disease and Osteoporosis An exploration of the intricate link between chronic lung ailments and osteoporosis.
AI Detection of Knee Osteoarthritis Recent use of artificial intelligence aiding knee osteoarthritis identification. Inflammatory Signalling in Rheumatoid Arthritis Covers the role of cytokines and chemokines in the context of rheumatoid arthritis. Vitamin D, Immune System, and Bone Health Unveils the vital implications of Vitamin D on the immune system and bone health. Bone Water and Hydration Effects A review of the impact of drugs on bone hydration status through the lens of bone water. Dietary Patterns and Rheumatoid Arthritis An analysis of the connection between dietary habits and rheumatoid arthritis. Quality of Life in Rheumatoid Arthritis Patients (Chapters 112-130): An examination of the self-perceived quality of life in Rheumatoid Arthritis patients, comparing South Asian and British White populations. This knowledge-rich treatise is a valuable resource for patients and their families battling these skeletal ailments. It's equally beneficial for medical students, orthopedists, researchers, and anyone eager to grasp the complexities of these widespread skeletal pathologies.
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Otolaryngology for the Pediatrician
Otolaryngology for the Pediatrician serves both as a primer as well as an instant reference for all medical practitioners caring for the pediatric patient. Ear, nose, and throat (ENT) diseases are very common in children and this e-book covers the vast majority of these conditions from an expert viewpoint with data published by respected medical professionals. Topics covered in this e-book include hearing loss, otitis media, neck masses and infections, sinusitis, stridor and many more. Readers with find actionable education needed to help care for their patients presented within simple, easy to read chapters.
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Outcomes Assessment in End - Stage Kidney Disease - Measurements and Applications in Clinical Practice
With an increase of the population of elderly people in modern society due to advances in medicine and healthcare facilities, there is also an increase in the incidence and duration of chronic illnesses. Similarly, advanced age is considered a significant determinant of depression and poor quality of life. Additionally, the provision of therapies relevant to chronic diseases addresses the issues beyond the concept of cure, bringing to the center the need for a dignified quality of life of patients. An increased interest in quality of life is observed in patients who suffer from chronic diseases, including those with end-stage kidney disease (ESKD). End-stage kidney disease patients have a high burden of disease affecting their quality of life and dramatically shortening their life expectancy. Therefore, exploring quality of life issues among such patients becomes an essential task in the management of this population. This volume is written by researchers with a well-rounded understanding of the characteristics and impact of ESKD and provides a penetrating practical discussion to date of alternative approaches for comprehensively measuring the burden of end-stage kidney disease. Outcomes Assessment in End-Stage Kidney Disease focuses on the impact of this complex and exacting condition on patients and those that care for them. It also examines the economic impact of ESKD and the healthcare policy implications of this disease. It also brings comprehensive and thoughtful insights into the issues confronted by patients with ESKD to readers interested in nursing or medical caregiving, geriatrics and health psychology.
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Ovarian Cancer-Challenges and Innovations
This informative book provides a wealth of information on ovarian cancer. The book opens with a discussion of contemporary management of this disease with commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies. This is followed by presentations on ovarian cancer pathology. A chapter is devoted to methods of drug discovery through a functional genomics approach, with gene expression microarray databases available in public data repositories such as Public Gene Expression Omnibus (GEO} and validation using immunohistochemistry or Ingenuity Pathway Analysis (IPA). Next, the book explores the psycho-social issues that may be encountered by an ovarian cancer patient, including commentary on pain, fertility, anxiety, depression, demoralization, caregiver burnout, and end-of-life. The final chapter represents a step out from mainstream medical practice and provides an exposition of the mind-body interaction and the powerful role of belief in the healing process, with discussions of the placebo effect, nocebo effect, and numerous research studies that demonstrate the tremendous influence of our beliefs on our bodies and well-being.
Key Features:
- Provides a holistic view of ovarian cancer
- Covers both conventional medical research topics and key social issues encountered by patients, caregivers and medical professionals.
- Explains cancer pathology and related concepts with the help of illustrations and notes on future directions
- Features commentary from experts in ovarian cancer treatment
- Written in a reader-friendly style suitable for a wide range of readers
Ovarian Cancer Challenges and Innovations is a comprehensive reference about ovarian cancer for medical students, residents, practitioners, healthcare support staff (nurses, physician assistants), medical researchers and scientists, as well as patients and interested laypersons seeking to improve their current knowledge of ovarian cancer
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Overall Aspects of Non-Traditional Glasses: Synthesis, Properties and Applications
The considerable proliferation of new glasses during the second half of the 20th century (germanate,
vanadate, bismuthate, tellurite, chalchogenide glasses, etc.) brought about the use the plural form of the
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generic glass denomination, in order to be able to index each emerging glass family by its proper name, as
well as to classify them methodically. Together with its great compositional versatility, the peculiar
characteristics of glass (non-crystalline structure with short-range order, continuous network with no
intergranular boundaries, isotropy, easy to be formed into a plastic state inside a wide temperature range)
allow for a freedom of design and adaptability that few materials are able to offer. All these circumstances
have contributed to the fact that, in the last seventy years, glass has acquired the multiple and varied
appearance of its new families, without losing neither its original image nor its soda-lime-silica traditional
composition, destined for the huge industrial manufacture of its conventional products.
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Oxygen Atom Transfer Reactions
CHEMICAL REACTION MECHANISMS Mechanisms of Oxidation Reactions: Volume 1
This book introduces readers to the fundamentals of oxygen atom transfer reactions. It also gives mechanistic insights into the redox processes occurring through the oxygen atom transfer reactions. It also includes information about catalytic activation of oxygen through enzymes and oxo-metallic complexes. All topics are explored in separate chapters. Key features: - reviews the basic mechanisms in redox processes involving oxo-atom transfer reactions. - presents progress in the biomimetic activation of dioxygen related to the catalytic oxidations by synthetic metal organic complexes. - covers an important class of metal-organic compounds - nickel-oxygen species - generated in catalytic oxidation processes as oxygen atom transfer agents. - explains the mechanistic aspects of the heterogeneous photochemical redox processes via oxo-atom transfer reactions - provides references for further reading It is a reference for both professional scientists in the fields of chemistry, biology and applied sciences, and for graduate and undergraduate students interested in understanding reaction mechanisms involving oxygen.
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Oxygen, the Breath of Life: Boon and Bane in Human Health, Disease, and Therapy
Oxygen is historically entwined from its discovery with radical applications as a panacea by charlatans and by daring men constructing bridges using underwater caissons. Oxygen has made possible the exploration of the depths of the oceans beginning with hard-hat diving suits and extending to scuba gear, underwater habitats and submarines as well as space exploration. Molecular oxygen is critically involved in health and disease in more ways than any other element. It is essential for metabolism of food to nourish our bodies. Understanding its biological and chemical nature helps us to understand the effects of exercise, vitamins and supplements, and drugs used for cancer therapies.
Oxygen, the Breath of Life is a comprehensive reference on the historical, biological, chemical and medical aspects of oxygen. Readers, both laymen and experts, will gain knowledge of the basics of oxygen chemistry, how it functions in the human body, the role of oxidants in the development of various diseases. Chapters contain historical notes which highlight the discoveries of pioneering researchers.
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Oxygen: High Enzymatic Reactivity of Reactive Oxygen Species
This book presents information about the high enzymatic reactivity of reactive oxygen species. Chapters in the book cover several aspects of the topic such as the sources, formation mechanisms, reaction centers, oxidation-reduction reactions, cellular respiration chemistry, enzymatic kinetics, mitochondrial and plastid electron transport chains, oxidation-reduction potential, reaction constants, reaction velocity and reaction mechanisms involved, cellular cytotoxicity, antioxidant defense mechanisms in plants and animals, response of plants to conditions of environmental stress, xenobiotics, and the thermodynamics inherent to oxygen metabolism. The book also features a chapter on flavonoids which highlights a paradoxical facet of the affinity of reactive oxygen species for enzymes. Flavonoids are mainly antioxidant molecules as they act as trappers of reactive oxygen species. The chapter informs readers about the metabolic pathways mediated by enzymes through wich flavonoids become promoters of these same reactive oxygen species. All chapters present the subject in a simple, analytical format, while highlighting the scientific evidence gathered by researchers so far. The volume is an interesting reference for scholars learning about the biochemistry and enzymology of oxygen and its free radical derivatives.
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Pain: Causes, Concerns and Consequences
Pain is a significant medical problem, as it is a factor in many diseases and debilitating conditions. The processing of pain in the body is a complex process which involves nerve signaling in the milieu of biochemical, molecular and genetic interactions occurring in the brain and other parts of the body. Pain, as a spokesperson of real and impending injury, outlives its usefulness as a warning signal and instead becomes chronic and excruciating. The transition of the realization of pain up to the cortical processing as a persistent condition represents an intricate process governed by the interaction of various factors. Research on humans and animals has led to the advent of personalized medicine where every patient can be treated according to the set of genes they possess. However, the genetic basis for pain has largely been undefined so far. Research on epigenetic alterations and micro-RNA (miRNA) in relation to the assessment and prevention of pain is still in infancy.
Pain: Causes, Concerns and Consequences focuses on pain in human diseases such as cardiac and non-cardiac disorders. This compendium on pain research offers basic information and useful updates on the pathology, genetics, and biomolecular pathways that cause pain. Additionally, readers will also learn about non-pharmacological therapies for pain. The monograph is a handy guide for medical students and doctors in different divisions such as oncology, surgery, neurology, psychiatry, psychology, physiotherapy and chiropractic care. The book also serves as a guide for life science researchers who are planning to develop methods to study pain in either a clinical or laboratory setting.
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Parasitic Diseases of Goats
Parasitic Diseases of Goats provides a comprehensive exploration of parasitic infections affecting goats and their impact on various organ systems. The book covers a wide range of parasitic diseases, including those affecting the gastrointestinal, respiratory, cardiovascular, nervous, and urogenital systems, as well as the liver, pancreas, skin, and musculoskeletal system. Diagnostic techniques and therapeutic approaches for managing these infections are also discussed in the chapters of this book.
This book is an essential resource for veterinarians, researchers, students, and professionals in parasitology and veterinary medicine. Key features include detailed descriptions of parasite-related diseases, their pathogenesis, diagnostic methods, and treatment strategies to improve goat health and management.
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Parasitic Weeds of Jordan: Species, Hosts, Distribution and Management
Root Parasites; Orobanchaceae, Santalaceae & Cynomoriaceae - Part 1
This book introduces the most recent research findings on selected parasitic weeds that occur in Jordan and are also spread in Middle Eastern countries. It is a valuable source of information for researchers, students as well as farmers, giving readers a better understanding of these regional parasites and their unusual growth patterns. The book set consists of two volumes. The first volume includes information about genera which are typically known as root parasites. These genera are Orobanchaceae, Santalaceae, and Cynomoriaceae families. The second volume covers stem parasites of the Cuscutaceae, Loranthaceae and Viscaceae families. The detailed information presented in this set makes this an essential reference on weeds and parasitic plants in Jordan and Middle Eastern regions.
Key Features:
- Chapters cover the biology, ecology, distribution, economic significance, host ranges, and control methods of a variety of regional weeds in an organized way
- It includes information on parasitic families, genera and species that are found in Jordanian flora and their hosts.
- It also provides coloured photos of weeds
- Presents the latest techniques for plant pest management
- Provides references for further reading
- Includes a glossary and appendix suitable for beginners
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Parasitic Weeds of Jordan: Species, Hosts, Distribution and Management
Part 2 - Stem Parasites; Cuscutaceae, Loranthaceae & Viscaceae
This book introduces the most recent research findings on selected parasitic weeds that occur in Jordan and are also spread in Middle Eastern countries. It is a valuable source of information for researchers, students as well as farmers, giving readers a better understanding of these regional parasites and their unusual growth patterns. The book set consists of two volumes. The first volume includes information about genera which are typically known as root parasites. These genera are Orobanchaceae, Santalaceae, and Cynomoriaceae families. The second volume covers stem parasites of the Cuscutaceae, Loranthaceae and Viscaceae families. The detailed information presented in this set makes this an essential reference on weeds and parasitic plants in Jordan and Middle Eastern regions.
Key Features:
- Chapters cover the biology, ecology, distribution, economic significance, host ranges, and control methods of a variety of regional weeds in an organized way
- It includes information on parasitic families, genera and species that are found in Jordanian flora and their hosts.
- It also provides coloured photos of weeds
- Presents the latest techniques for plant pest management
- Provides references for further reading
- Includes a glossary and appendix suitable for beginners.
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Passive Location Method Based on Phase Difference Measurement
Passive Location Method Based on Phase Difference Measurement presents groundbreaking information for developing passive positioning technologies. The author has put forward a series of innovative solutions from the perspective of engineering application theory with the aim of giving a basic understanding of the application of unambiguous phase difference localization techniques for long-range passive detection.
On the basis of the existing linear solution of the double basis path difference positioning equation and the analysis of its intrinsic properties, this book starts from the study of the phase difference measurement method of the phase difference change rate, puts forward the concept of the differential function of the path difference per unit wavelength length and also discovers its jump law. It provides a possible way to solve the problem of unambiguous phase difference measurement. These results are of great significance to the development of passive localization techniques based on unambiguous phase difference measurement.
Key Features:
- Sequentially presents theoretical frameworks to build the readers knowledge for better understanding the topics
- Presents a variety of unique method for solving kinematic positioning parameters and Doppler signal parameters by using unambiguous phase difference measurement.
- Presents a variety of direction-finding and ranging methods based on short baseline array and using unambiguous phase difference measurement technology, and exhibits the method of constructing long baseline two-station direction finding and ranging with short baseline array
- Presents a variety of two-station passive positioning methods based on angle measurement which are beneficial to improve the positioning accuracy on the basis of studying the relationship between the phase difference and angle
- Presents the means to convert Doppler detection to the non-fuzzy phase difference measure, for the localization problem in which it is difficult to use the phase difference localization equation directly, since the accuracy of the phase difference measurement is better than that of the Doppler frequency difference
- Presents a variety of new positioning methods and several novel concepts while demonstrating the theoretical exploration of passive location problem based on unambiguous phase difference measurement
This reference is a resource for scholars, engineers and technicians involved in radio positioning research and the improvement of radar, satellite navigation systems, unmanned systems and Internet of Things infrastructure.
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Pathogenic Escherichia coli in Latin America
Pathogenic Escherichia coli are known to be a common cause of diarrheal disease a common cause of frequently occurring bacterial infections in children and adults in developing countries. It poses a significant problem in Latin America. Pathogenic Escherichia coli in Latin America presents current information on understanding pathogenic E. coli in Latin America and outlines prospects for future research in this region. It features a unique, comprehensive analysis of the most common categories of E. coli associated with diarrheal illness in Latin America. The aim of this book is to help epidemiologists in this region to learn about molecular mechanisms of E. coli pathogenesis along with its diagnosis, host immune responses, animal reservoirs and epidemiology. In addition, the authors discuss the current situation of E. coli in representative countries, including Argentina, Brazil, Chile, Mexico and Peru.
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Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts
Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts is a comprehensive guide that explores the fundamental aspects, synthesis methods, and various applications of nanomaterials derived from plants. This book is designed for postgraduate researchers, engineers, and scientists in the fields of materials science, biotechnology, and chemical engineering, as well as other disciplines involved in nanomaterial production and applications.
The book delves into different plant-mediated nanomaterials, analyzing their synthesis mechanisms and discussing the regulation and application prospects of plant synthesis. It covers topics such as nanocellulose, biochar materials, plant exosomes, polyphenol nanoparticles, and the phytotoxicity and uptake of nanomaterials by plants. Additionally, it explores the research progress and applications of plant virus nanoparticles in the medical field, including drug delivery, molecular imaging, and vaccine preparation. Readers will be familiarized with the synthetic methods, characterization, and applications of green nanomaterials, paving the way for future studies on plants and their phytochemical constituents.
With its comprehensive coverage of plant-derived nanomaterials and their diverse applications, Pathways to Green Nanomaterials: Plants as Raw Materials, Reducing Agents and Hosts serves as a valuable resource for researchers seeking to understand the potential of plants as sustainable sources for nanomaterial production.
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Pediatric Anesthesia: A Guide for the Non-Pediatric Anesthesia Provider Part I
Pediatric Anesthesia: A Guide for the Non-Pediatric Anesthesia is a comprehensive, contemporary reference that addresses all aspects of pediatric anesthesia. Both students and medical practitioners - novice and experienced - will find invaluable educational and practical information in this book. The book covers the subject in two parts.
Part I covers basic information about pediatric and neonatal anatomy and physiology, pharmacology, emergency room and operating room procedures and surgery. Chapters on general anesthetic procedures in emergency rooms, operational theatres and common surgeries.
Part II covers advanced topics for practicing healthcare professionals which include anesthesia for patients with a range of common and uncommon comorbidities, considerations for critically-ill patients, genetic disorders, pain management, COVID-19 guidelines for anesthesia, patient safety and research.
Key features:
- Basic and advanced information about pediatric and neonatal anesthesia covered in 25 chapters over two parts
- Simple and organized presentation for learners
- Contributions by expert clinicians and researchers
- Special topics included such as considerations for patients with comorbidities and genetic disorders
- References for further reading
- Detailed illustrations and tables
The text is an essential reference for scholars and professionals affiliated with general anesthesiology and surgery specialties at all levels who want to understand anesthesia for pediatric patients.
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Pediatric Anesthesia: A Guide for the Non-Pediatric Anesthesia Provider Part II
Pediatric Anesthesia: A Guide for the Non-Pediatric Anesthesia is a comprehensive, contemporary reference that addresses all aspects of pediatric anesthesia. Both students and medical practitioners - novice and experienced - will find invaluable educational and practical information in this book. The book covers the subject in two parts.
Part I covers basic information about pediatric and neonatal anatomy and physiology, pharmacology, emergency room and operating room procedures and surgery. Chapters on general anesthetic procedures in emergency rooms, operational theatres and common surgeries.
Part II covers advanced topics for practicing healthcare professionals which include anesthesia for patients with a range of common and uncommon comorbidities, considerations for critically-ill patients, genetic disorders, pain management, COVID-19 guidelines for anesthesia, patient safety and research.
Key features:
- Basic and advanced information about pediatric and neonatal anesthesia covered in 25 chapters over two parts
- Simple and organized presentation for learners
- Contributions by expert clinicians and researchers
- Special topics included such as considerations for patients with comorbidities and genetic disorders
- References for further reading
- Detailed illustrations and tables
The text is an essential reference for scholars and professionals affiliated with general anesthesiology and surgery specialties at all levels who want to understand anesthesia for pediatric patients.
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Pediatric Orthodontics: Theory and Practice
Recent Advances in Dentistry: Volume 2
Pediatric Orthodontics: Theory and Practice provides readers (practicing dentists, medical residents, pediatric specialists) with the knowledge to manage cases in regular pediatric orthodontic practice by presenting answers to specific problems related to diagnosis, clinical findings and treatment methods. It is also an essential supplement for the post-graduate student's dental curriculum. The book's problem based format allows readers to test and improve their knowledge about relevant topics which include craniofacial growth, facial aesthetics, musculoskeletal structure, occlusal guidance, maxillary transverse discrepancy, dental anomalies, tooth impaction, and, class II and class III malocclusions.
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Perhalopyridines: Synthesis and Synthetic Utility
Halogenated pyridines can be used as interesting starting materials in a wide range of organic synthesis methods. Substituted pyridine compounds are used generally as starting materials in the nucleophilic substitution reactions and have unique scaffolds for the construction of other heterocyclic and macrocyclic compounds. They also have important medicinal properties. Due to synthetic difficulties in the synthesis of the highly substituted pyridine derivatives from pyridine itself, perhalopyridines have a special importance in this regard. This book covers the synthetic reactions and applications of perhalopyridines. An introductory chapter introduces the reader to the physical and chemical properties of halopyridines, followed by 3 chapters which focus on pentafluoropyridine, pentachloropyridine and pentabromopyridine, respectively. The focused chapters provide information about synthetic methods and relevant nucleophilic reactions for each of the listed perhalopyridines and their derivatives. The book is a quick reference on perhalopyridines for students of applied chemistry, organic chemistry and chemical engineering.
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Perinatal Cardiology-Part 1
In Perinatal Cardiology, fetal cardiology experts provide key information on tools for fetal evaluation through echocardiography / cardiac ultrasonography, with a primary focus on the nature and prenatal detection of structural and functional cardiac heart defects (CHDs). In this two-part book, readers will find details about different types of fetal cardiac abnormalities along with important updates on the diagnosis, management, planning delivery, and postnatal treatment in CHD cases. This information is supplemented with guidelines for the clinical management of patients with a fetus affected by cardiovascular defects, and surgical procedures in neonates.
Key Features:
-presents information gathered by experts in perinatal cardiology, organized into 26 topic-based chapters
- explores the cardiac development, fetal cardiovascular hemodynamics, genetic and environmental factors associated with congenital heart defects (CHD), perinatal management, planning delivery, and postnatal treatment of newborns with CHD
- presents information about normal cardiac functions and heart defects to give readers a clear and detailed picture of abnormal cardiac function
- presents information about perinatal ultrasound physiology
- gives practical guidelines for ultrasound and echography parameters required for evaluating fetal heart anatomy and diagnosing diseases
- includes a new system of classifying prenatal CHDs based on the stratification of the risk level of care
- features a straightforward and accessible style of presentation suitable for all readers
- provides references in each chapter for further reading
Part 1 of this two-part set covers the basics of perinatal cardiology which chapters that introduce readers to CHD classification, fetal heart and placental physiology and pathology, diagnosis of fetal cardiac malposition and anomalies and some congenital heart defects such as septal defects, cardiac anomalies of the left and right sides, conotruncal anomalies and aortic arch anomalies.
Perinatal Cardiology is an essential reference for postgraduate medical students seeking to improve their knowledge of fetal and pediatric cardiology as part of their residency and professional training. The book equips readers with the information necessary to understand the role of the perinatal cardiologist and goes further to facilitate the ability to perform adequate risk assessments for fetal CHD.
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Perinatal Cardiology-Part 2
In Perinatal Cardiology, fetal cardiology experts provide key information on tools for fetal evaluation through echocardiography / cardiac ultrasonography, with a primary focus on the nature and prenatal detection of structural and functional cardiac heart defects (CHDs). In this two-part book, readers will find details about different types of fetal cardiac abnormalities along with important updates on the diagnosis, management, planning delivery, and postnatal treatment in CHD cases. This information is supplemented with guidelines for the clinical management of patients with a fetus affected by cardiovascular defects, and surgical procedures in neonates.
Key Features:
-presents information gathered by experts in perinatal cardiology, organized into 26 topic-based chapters
- explores the cardiac development, fetal cardiovascular hemodynamics, genetic and environmental factors associated with congenital heart defects (CHD), perinatal management, planning delivery, and postnatal treatment of newborns with CHD
- presents information about normal cardiac functions and heart defects to give readers a clear and detailed picture of abnormal cardiac function
- presents information about perinatal ultrasound physiology
- gives practical guidelines for ultrasound and echography parameters required for evaluating fetal heart anatomy and diagnosing diseases
- includes a new system of classifying prenatal CHDs based on the stratification of the risk level of care
- features a straightforward and accessible style of presentation suitable for all readers
- provides references in each chapter for further reading
Part 2 of this two-part set delves into different fetal anomalies such as ventricular inflow anomalies, myocardial and pericardial diseases, cardiac tumors, extra-cardiac conditions, cardiac failure, and environmental factors associated with CHD. The latter chapters cover clinical topics such as labor management for patients bearing a child with CHD, fetal cardiac interventions, clinical management of neonates with CHD and postnatal surgery.
Perinatal Cardiology is an essential reference for postgraduate medical students seeking to improve their knowledge of fetal and pediatric cardiology as part of their residency and professional training. The book equips readers with the information necessary to understand the role of the perinatal cardiologist and goes further to facilitate the ability to perform adequate risk assessments for fetal CHD.
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Personalized Immunotherapy for Tumor Diseases and Beyond
This book introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for immunotherapy of patients. The book introduces readers to some basic concepts which lay the foundation for personalized immunotherapy: the development of a major histocompatibility complex (MHC), the genome profile of T cells and tumor cells, and genome-wide association studies. Chapters also cover special topics such as new immunoassay methods related to personalized immunotherapy and targeted immunotherapy which are geared towards familiarizing readers with current research practices. Focusing on the central theme of personalized immunotherapy, the authors provide a wealth of information about T-cell screening, tumor neoantigen cloning, primary tumor cell culture for T-cell cloning, bioinformatics strategies for understanding T-cell and primary tumor cell biology and function, and new developments in research on adoptive T-cell immunotherapy. These developments include T-cell gene therapy and T-cell gene editing, transgenic T-cells for increasing affinity to tumor cells such as CAR T-cells and TCR T-cells, and the systematic modeling of polyclonal specific T-cells and biobank technology.
Key Features:
- Introduces readers to basic concepts in personalized medicine and immunotherapy
- Presents current information about immunological assays used in research
- Presents an overview of T cell immunotherapy and cloning techniques
- Presents an overview of tumor cell bioinformatics and its role in immunotherapy
- Includes new developments and references for personalized immunotherapy techniques (T-cell gene therapy and T-cell gene editing, transgenic T-cells which target CAR T-cells and TCR T-cells, and polyclonal T-cell modeling)
- Includes a section on biobanking
- Presents information in an easy-to-read format for a wide range of readers
- Brings contributions from experts with over 30 years of experience in personalized immunotherapy
Personalized Immunotherapy for Tumor Diseases and Beyond is an ideal handbook for medical professionals and students involved in personalized medicine, immunology and oncology. General readers interested in the new developments in these fields will also benefit from the information provided.
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Petrogenic Polycyclic Aromatic Hydrocarbons in the Aquatic Environment: Analysis, Synthesis, Toxicity and Environmental Impact
Although a lot is known about the influence of Polycyclic Aromatic Hydrocarbons (PAHs) on the marine environment, there are still many unanswered questions. Petrogenic Polycyclic Aromatic Hydrocarbons in the Aquatic Environment is a monograph that sums up basic knowledge about this topic while highlighting current research practices useful in studying the aquatic environment. It starts with an introduction to effect of PAH in the marine environment. It then proceeds to provide information on techniques to monitor PAH levels and investigate the affected environment in order to control the subsequent negative effects. Chapters also detail the carcinogenic and endocrine effects of PAHs on fish as well as the degradation of PAHs by microorganisms. This monograph is a useful reference for environmental science students and professionals learning about the role of PAH in the marine environment.
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